28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

Base Information

Chemical Name:28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin
CAS No.:1104398-61-9
Molecular Formula:C₇₂H₈₈O₉Si
Molecular Weight:1125.57
Hs Code.:

Synonyms:28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

Suppliers and Price of 28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

There total 3 articles about 28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 2,3,4-tri-O-benzoyl-α,β-L-arabinopyranosyl trichloroacetimidate

: 954382-10-6
28-O-tert-butyldiphenylsilylbetulin

: 1104398-61-9
28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

Guidance literature:: 2,3,4-tri-O-benzoyl-α,β-L-arabinopyranosyl trichloroacetimidate; 28-O-tert-butyldiphenylsilylbetulin; In dichloromethane; at 20 ℃; for 0.333333h; Molecular sieve;

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -40 ℃; for 0.5h; Molecular sieve;
DOI:10.1016/j.carres.2016.01.010

Reference yield: 71.0%

: 954382-10-6
28-O-tert-butyldiphenylsilylbetulin

: 247017-34-1
2,3,4-tri-O-benzoyl-β-L-arabinopyranosyl trichloroacetimidate-⁴C₁

: 1104398-61-9
28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 2.5h; Molecular sieve;
DOI:10.1021/np800579x

Reference yield:

: 473-98-3
betulin

: 58479-61-1
tert-butylchlorodiphenylsilane

: 1104398-61-9
28-O-tert-butyldiphenylsilyl-3β-O-(2,3,4-tri-O-benzoyl-α-L-arabinopyranosyl)betulin

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1H-imidazole; dmap / tetrahydrofuran / 16 h / Reflux

2.1: dichloromethane / 1 h / 20 °C / Inert atmosphere; Molecular sieve

2.2: 2.5 h / 20 °C / Inert atmosphere; Molecular sieve

With 1H-imidazole; dmap; In tetrahydrofuran; dichloromethane;