Urea, 1,3-bis(1-naphthyl)-2-thio-

Base Information

• Chemical Name: Urea, 1,3-bis(1-naphthyl)-2-thio-
• CAS No.: 1240-37-5
• Molecular Formula: C21H16 N2 S
• Molecular Weight: 328.437
• Hs Code.: 2930909090
• European Community (EC) Number: 214-986-7
• NSC Number: 74417
• UNII: LC83DR4KBB
• DSSTox Substance ID: DTXSID70154185
• Nikkaji Number: J40.770D
• ChEMBL ID: CHEMBL1884542
• Mol file: 1240-37-5.mol

Synonyms:1240-37-5;Urea, 1,3-bis(1-naphthyl)-2-thio-;Di-1-naphthylthiourea;1,3-dinaphthalen-1-ylthiourea;Thiourea, N,N'-di-1-naphthalenyl-;1,3-Di-1-naphthyl-2-thiourea;Di-1-naphthyl thiourea;Urea, 1,3-di-1-naphthyl-2-thio-;N,N'-Di-alpha-naphthylthiourea;1,3-Bis(1-naphthyl)-2-thiourea;EINECS 214-986-7;NSC 74417;LC83DR4KBB;1,3-Di-1-naphthylthiourea;BRN 1008875;1,3-Bis(1-naphthyl)thiourea;AI3-24028;MLS002693898;N,N'-Di-.alpha.-naphthylthiourea;NSC-74417;2-12-00-00696 (Beilstein Handbook Reference);NSC74417;UNII-LC83DR4KBB;NCIOpen2_009023;SCHEMBL1275812;CHEMBL1884542;C21H16N2S;Thiourea,N'-di-1-naphthalenyl-;Urea,3-di-1-naphthyl-2-thio-;DTXSID70154185;HMS3079L11;Urea,3-bis(1-naphthyl)-2-thio-;N,N'-DI-1-NAPHTHYLTHIOUREA;C21-H16-N2-S;STK993613;WLN: L66J BMYUS&M- BL66J;AKOS002271792;N,N'-DI-1-NAPHTHALENYLTHIOUREA;1,3-DI-.ALPHA.-NAPHTHYLTHIOUREA;SMR001559839;LS-159130

Chemical Property of Urea, 1,3-bis(1-naphthyl)-2-thio-

Chemical Property:

• Vapor Pressure: 3.85E-11mmHg at 25°C
• Boiling Point: 525.6°Cat760mmHg
• Flash Point: 271.7°C
• PSA: 56.15000
• Density: 1.335g/cm³
• LogP: 5.94790
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 328.10341969
• Heavy Atom Count: 24
• Complexity: 400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2NC(=S)NC3=CC=CC4=CC=CC=C43

Technology Process of Urea, 1,3-bis(1-naphthyl)-2-thio-

There total 13 articles about Urea, 1,3-bis(1-naphthyl)-2-thio- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

carbon disulfide (75-15-0,12122-00-8) + 1-amino-naphthalene (134-32-7) → N,N'-bis(1-naphthyl)thiourea (1240-37-5)

Guidance literature:

With Cyclohexyl isocyanide; In ethanol; at 20 ℃; for 3h;

DOI:10.1080/17415993.2012.724419

Reference yield: 90.0%

1-amino-naphthalene (134-32-7) + thiourea (17356-08-0) → N,N'-bis(1-naphthyl)thiourea (1240-37-5)

Guidance literature:

With PEG-400; In water; for 0.0333333h; microwave irradiation;

DOI:10.1080/104265090968082

Reference yield: 85.0%

C11H8NS2(1-)*C6H15N*H(1+) → N,N'-bis(1-naphthyl)thiourea (1240-37-5)

Guidance literature:

In ethyl acetate; at 77 ℃;

DOI:10.1080/10426507.2016.1223075

upstream raw materials:

carbon disulfide

1-amino-naphthalene

bis(carboxymethyl)trithiocarbonate

N-(naphthalen-1-ylcarbamothioyl)benzamide

Downstream raw materials:

naphthalen-1-yl-(3-naphthalen-1-yl-4-phenyl-3H-thiazol-2-ylidene)-amine

5,5-Bis-(2-hydroxy-phenyl)-1,3-di-naphthalen-1-yl-2-thioxo-imidazolidin-4-one

CNS 1076

cis-tetracarbonyl(sym-di-α-naphthylthiourea)(triphenylarsine)tungsten(0)

Refernces

• 1、 Chen, Ling,Dong, Yibo,Wu, Yangjie,Yang, Jinchen,Zhang, Jinli. "Di-tert-butyl peroxide (DTBP)-mediated synthesis of symmetrical N,N′-disubstituted urea/thiourea motifs from isothiocyanates in water". supporting information. . Retrieved 2021/12/01.
• 2、 üng?ren, ?evket Hakan,S?r?a, Fatih. "Novel self-condensation of ammonium dithiocarbamates leading to symmetrical substituted thioureas". supporting information. p. 28 - 33. Retrieved 2016/12/24.