(1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

Base Information

Chemical Name:(1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol
CAS No.:232280-13-6
Molecular Formula:C₃₀H₅₂O₅Si
Molecular Weight:520.825
Hs Code.:

Synonyms:(1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

Suppliers and Price of (1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

There total 13 articles about (1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-5-(4-Methoxy-benzyloxy)-2-((S)-3-methyl-2-methylene-4-triisopropylsilanyloxy-butoxy)-pentanoic acid

: 232280-13-6
(1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

Guidance literature:: Multi-step reaction with 4 steps

1: NEt₃ / diethyl ether / Ambient temperature

2: diethyl ether / Ambient temperature

3: Rh₂(HNCOCF₃)4 / CH₂Cl₂ / Ambient temperature

4: CH₂Cl₂ / -78 - 5 °C

With triethylamine; tetra(trifluoroacetamidato)dirhodium(II); In diethyl ether; dichloromethane;

Reference yield:

: 232280-19-2
(2R,3R)-1,2-O-isopropylidene-6-[(4-methoxybenzyl)oxy]-3-{(3S)-3-methyl-2-methylene-4-[(triisopropylsilyl)oxy]butoxy}hexane-1,2-diol

: 232280-13-6
(1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

Guidance literature:: Multi-step reaction with 7 steps

1: PPTS / ethane-1,2-diol; tetrahydrofuran; CH₂Cl₂ / Heating

2: NaIO₄, H₂O / tetrahydrofuran

3: PDC / dimethylformamide / Ambient temperature

4: NEt₃ / diethyl ether / Ambient temperature

5: diethyl ether / Ambient temperature

6: Rh₂(HNCOCF₃)4 / CH₂Cl₂ / Ambient temperature

7: CH₂Cl₂ / -78 - 5 °C

With sodium periodate; dipyridinium dichromate; water; pyridinium p-toluenesulfonate; triethylamine; tetra(trifluoroacetamidato)dirhodium(II); In tetrahydrofuran; diethyl ether; dichloromethane; ethylene glycol; N,N-dimethyl-formamide;

Reference yield:

: 13154-24-0
triisopropylsilyl chloride

: 232280-13-6
(1R,6S)-1,4-anhydro-3,5,6-trideoxy-1-{3-[(4-methoxybenzyl)oxy]propyl}-6-methyl-2-C-methyl-5-methylene-7-O-(triisopropylsilyl)-D-xylo-heptitol

Guidance literature:: Multi-step reaction with 11 steps

1: 99 percent / imidazole / dimethylformamide / Ambient temperature

2: 98 percent / CeCl₃ / tetrahydrofuran / -70 - 20 °C

3: 97 percent / pyrrolidone hydrotribromide, pyridine / tetrahydrofuran / -10 - 20 °C

4: 90 percent / NaH / tetrahydrofuran

5: PPTS / ethane-1,2-diol; tetrahydrofuran; CH₂Cl₂ / Heating

6: NaIO₄, H₂O / tetrahydrofuran

7: PDC / dimethylformamide / Ambient temperature

8: NEt₃ / diethyl ether / Ambient temperature

9: diethyl ether / Ambient temperature

10: Rh₂(HNCOCF₃)4 / CH₂Cl₂ / Ambient temperature

11: CH₂Cl₂ / -78 - 5 °C

With pyridine; 1H-imidazole; sodium periodate; dipyridinium dichromate; cerium(III) chloride; pyrrolidone hydrotribromide; water; pyridinium p-toluenesulfonate; sodium hydride; triethylamine; tetra(trifluoroacetamidato)dirhodium(II); In tetrahydrofuran; diethyl ether; dichloromethane; ethylene glycol; N,N-dimethyl-formamide;