4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl

Base Information

• Chemical Name: 4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl
• CAS No.: 408366-69-8
• Molecular Formula: C₃₈H₃₇N₃O₄
• Molecular Weight: 599.729
• Mol file: 408366-69-8.mol

Synonyms:4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl

Chemical Property of 4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl

There total 1 articles about 4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-Butyl 4-aminophenyl[2-(2-pyridinyl)ethyl]carbamate (408365-61-7) + 4'-(benzyloxy)-[1,1'-biphenyl]-2-carboxylic acid (167627-28-3) + ethyl acetate n-hexane → 4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl (408366-69-8)

Guidance literature:

With thionyl chloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide; toluene;

Reference yield:

4-benzyloxy-2'-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-1,1'-biphenyl (408366-69-8) + ethyl acetate n-hexane → 2-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-4'-hydroxy-1,1'-biphenyl (408366-71-2)

Guidance literature:

palladium; In methanol; ethyl acetate;

upstream raw materials:

tert-Butyl 4-aminophenyl[2-(2-pyridinyl)ethyl]carbamate

4'-(benzyloxy)-[1,1'-biphenyl]-2-carboxylic acid

Downstream raw materials:

2-[(4-{(tert-butoxycarbonyl)[2-(2-pyridinyl)ethyl]amino}anilino)carbonyl]-4'-hydroxy-1,1'-biphenyl