2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

Base Information

• Chemical Name: 2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal
• CAS No.: 1332330-01-4
• Molecular Formula: C₂₆H₃₈O₁₀S
• Molecular Weight: 542.648
• Mol file: 1332330-01-4.mol

Synonyms:2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

Chemical Property of 2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal

There total 1 articles about 2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-decanoyl chloride (112-13-0) → 2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal (1332330-01-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 48.25 h / 0 - 20 °C

2: N,N-dimethyl-formamide / 12 h / 100 °C

With pyridine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2011.06.090

Reference yield: 49.0%

2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal (1332330-01-4) → 2,5-anhydro-3-azido-6-O-benzoyl-4-O-decanoyl-3-deoxy-D-allose ethylene acetal (1332330-03-6)

Guidance literature:

With sodium azide; In dimethyl sulfoxide; at 110 ℃; for 27h;

DOI:10.1016/j.tet.2011.06.090

Reference yield:

2,5-anhydro-6-O-benzoyl-4-O-decanoyl-3-O-methanesulfonyl-D-glucose ethylene acetal (1332330-01-4) → C23H32N4O6

Guidance literature:

Multi-step reaction with 3 steps

1: sodium azide / dimethyl sulfoxide / 27 h / 110 °C

2: hydrogenchloride; water; trifluoroacetic acid / 216 h / 4 °C

3: hydroxylamine hydrochloride; sodium acetate / ethanol; dichloromethane / 2 h / 20 °C

With hydrogenchloride; sodium azide; hydroxylamine hydrochloride; water; sodium acetate; trifluoroacetic acid; In ethanol; dichloromethane; dimethyl sulfoxide;

DOI:10.1016/j.tet.2011.06.090

upstream raw materials:

n-decanoyl chloride

Downstream raw materials:

2,5-anhydro-3-azido-6-O-benzoyl-4-O-decanoyl-3-deoxy-D-allose ethylene acetal

2,5-anhydro-3-azido-6-O-benzoyl-4-O-decanoyl-3-deoxy-D-allononitrile

2,5-anhydro-6-O-benzoyl-3-decanamido-3-deoxy-D-allonothioamide

ethyl 2-(5-O-benzoyl-2-decanamido-2-deoxy-β-D-ribofuranosyl)thiazole-4-carboxylate