bis-γ-phenylpropargyl sulfone

Base Information

• Chemical Name: bis-γ-phenylpropargyl sulfone
• CAS No.: 175439-15-3
• Molecular Formula: C₁₈H₁₄O₂S
• Molecular Weight: 294.374
• Mol file: 175439-15-3.mol

Synonyms:bis-γ-phenylpropargyl sulfone

Chemical Property of bis-γ-phenylpropargyl sulfone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis-γ-phenylpropargyl sulfone

There total 5 articles about bis-γ-phenylpropargyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

bis-γ-phenylpropargyl sulfide (13225-60-0) → bis-γ-phenylpropargyl sulfone (175439-15-3)

Guidance literature:

With Oxone; In dichloromethane;

DOI:10.1016/0040-4039(95)02345-3

Reference yield: 42.0%

bis-γ-phenylpropargyl sulfoxide (269717-71-7) → bis-γ-phenylpropargyl sulfone (175439-15-3)

Guidance literature:

With potassium peroxomonosulfate; In methanol; water; at 20 ℃; for 96h;

DOI:10.1016/S0040-4020(01)00923-1

Reference yield:

1-bromo-3-phenylprop-2-yne (1794-48-5) → bis-γ-phenylpropargyl sulfone (175439-15-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / Na₂S / methanol / 2 h / 20 °C

2: 89 percent / Oxone / CH₂Cl₂ / 50 °C

With sodium sulfide; Oxone; In methanol; dichloromethane;

DOI:10.1039/b207296n

upstream raw materials:

bis-γ-phenylpropargyl sulfide

bis-γ-phenylpropargyl sulfoxide

3-Phenyl-2-propyn-1-ol

1-bromo-3-phenylprop-2-yne

Downstream raw materials:

cis-1,6-diphenyl-3-hexene-1,5-diyne

trans-1,6-Bis(phenyl)hexa-1,5-diyn-3-ene

C₁₈H₁₄O₃S