Technology Process of Benzyl-O-(2,3,4-tri-O-benzoyl-6-desoxy-β-D-galactopyranosyl)-(1->3)-2-acetamido-4,6-di-O-acetyl-2-desoxy-α-D-galactopyranosid
There total 13 articles about Benzyl-O-(2,3,4-tri-O-benzoyl-6-desoxy-β-D-galactopyranosyl)-(1->3)-2-acetamido-4,6-di-O-acetyl-2-desoxy-α-D-galactopyranosid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 92 percent / 70 percent HClO4 / 2 h
2: 78 percent / piperidine / tetrahydrofuran / 18 h / Ambient temperature
3: 95 percent / 1,5-diazabocyclo<5.4.0>undec-5-ene / CH2Cl2 / 3 h / Ambient temperature
4: 1.) molecular sieves 4 Angstroem, 2.) trimethylsilyl triflate / 1.) dichloromethane, 1 h, 2.) r.t., 5 h
5: 60 percent aq. acetic acid / 2 h / 40 °C
6: pyridine / 48 h
With
piperidine; pyridine; perchloric acid; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; acetic acid; 1,5-Diazabicyclo[5.4.0]undec-5-ene;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 78 percent / molecular sieves 4 Angstroem, SnCl4 / CH2Cl2 / 2 h / -20 °C
2: 0.1 N methanolic NaOMe / methanol / 3 h
3: pyridine / 10 h
4: 1.) molecular sieves 4 Angstroem, 2.) dimethyl(methylthio)sulfonium triflate / 1.) dichloromethane, 1 h, 2.) r.t., 3 h
5: 60 percent aq. acetic acid / 2 h / 40 °C
6: pyridine / 48 h
With
pyridine; 4 A molecular sieve; sodium methylate; tin(IV) chloride; acetic acid; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate;
In
methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 0.1 N methanolic NaOMe / methanol / 3 h
2: pyridine / 10 h
3: 1.) molecular sieves 4 Angstroem, 2.) dimethyl(methylthio)sulfonium triflate / 1.) dichloromethane, 1 h, 2.) r.t., 3 h
4: 60 percent aq. acetic acid / 2 h / 40 °C
5: pyridine / 48 h
With
pyridine; 4 A molecular sieve; sodium methylate; acetic acid; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate;
In
methanol;
