Technology Process of C21H31NO4
There total 7 articles about C21H31NO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium carbonate;
In
dichloromethane; water;
for 0.5h;
Alkaline conditions;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: sodium hydrogencarbonate / tetrahydrofuran; water / 0.5 h
1.2: 168 h
1.3: pH 3
2.1: hydrogen / palladium 10% on activated carbon / methanol / 1 h
3.1: potassium carbonate / DMF (N,N-dimethyl-formamide) / 0.33 h
3.2: 3 h / 20 °C
4.1: hydrogenchloride / 1,4-dioxane
5.1: dichloromethane
6.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane / 0.83 h / -78 °C
6.2: 2.5 h / -78 - 0 °C
6.3: 1 h
7.1: sodium carbonate / dichloromethane; water / 0.5 h / Alkaline conditions
With
hydrogenchloride; hydrogen; sodium hydrogencarbonate; sodium carbonate; potassium carbonate; lithium diisopropyl amide;
palladium 10% on activated carbon;
In
tetrahydrofuran; 1,4-dioxane; methanol; DMF (N,N-dimethyl-formamide); n-heptane; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: hydrogen / palladium 10% on activated carbon / methanol / 1 h
2.1: potassium carbonate / DMF (N,N-dimethyl-formamide) / 0.33 h
2.2: 3 h / 20 °C
3.1: hydrogenchloride / 1,4-dioxane
4.1: dichloromethane
5.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane / 0.83 h / -78 °C
5.2: 2.5 h / -78 - 0 °C
5.3: 1 h
6.1: sodium carbonate / dichloromethane; water / 0.5 h / Alkaline conditions
With
hydrogenchloride; hydrogen; sodium carbonate; potassium carbonate; lithium diisopropyl amide;
palladium 10% on activated carbon;
In
tetrahydrofuran; 1,4-dioxane; methanol; DMF (N,N-dimethyl-formamide); n-heptane; dichloromethane; water;