Technology Process of ethyl (2S,3R)-3-benzamido-2-propylpentanoate
There total 8 articles about ethyl (2S,3R)-3-benzamido-2-propylpentanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium periodate / water; tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
2: tetrahydrofuran / 1 h / 20 °C
3: hydrogen; palladium 10% on activated carbon / ethyl acetate / 1 h / 20 °C
With
sodium periodate; palladium 10% on activated carbon; hydrogen;
In
tetrahydrofuran; water; ethyl acetate;
2: |Wittig Olefination;
DOI:10.1002/ejoc.201301281
- Guidance literature:
-
Multi-step reaction with 7 steps
1: Candida antarctica lipase B; water / tert-butyl methyl ether / 4.5 h / 80 °C / Resolution of racemate; Enzymatic reaction
2: hydrogenchloride / 1 h / 0 °C
3: water; sodium hydroxide / toluene / 1 h / 0 °C
4: osmium(VIII) oxide; 4-methylmorpholine N-oxide / acetone / 8 h / 20 °C
5: sodium periodate / water; tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
6: tetrahydrofuran / 1 h / 20 °C
7: hydrogen; palladium 10% on activated carbon / ethyl acetate / 1 h / 20 °C
With
hydrogenchloride; Candida antarctica lipase B; sodium periodate; osmium(VIII) oxide; palladium 10% on activated carbon; water; hydrogen; 4-methylmorpholine N-oxide; sodium hydroxide;
In
tetrahydrofuran; tert-butyl methyl ether; water; ethyl acetate; acetone; toluene;
6: |Wittig Olefination;
DOI:10.1002/ejoc.201301281
