Technology Process of ethyl (1S,2S,3R,4S)-2-benzamido-3,4-dihydroxycyclopentanecarboxylate
There total 5 articles about ethyl (1S,2S,3R,4S)-2-benzamido-3,4-dihydroxycyclopentanecarboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
osmium(VIII) oxide; 4-methylmorpholine N-oxide;
In
acetone;
at 20 ℃;
for 8h;
DOI:10.1002/ejoc.201301281
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Candida antarctica lipase B; water / tert-butyl methyl ether / 4.5 h / 80 °C / Resolution of racemate; Enzymatic reaction
2: hydrogenchloride / 1 h / 0 °C
3: water; sodium hydroxide / toluene / 1 h / 0 °C
4: osmium(VIII) oxide; 4-methylmorpholine N-oxide / acetone / 8 h / 20 °C
With
hydrogenchloride; Candida antarctica lipase B; osmium(VIII) oxide; water; 4-methylmorpholine N-oxide; sodium hydroxide;
In
tert-butyl methyl ether; acetone; toluene;
DOI:10.1002/ejoc.201301281
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydrogenchloride / 1 h / 0 °C
2: water; sodium hydroxide / toluene / 1 h / 0 °C
3: osmium(VIII) oxide; 4-methylmorpholine N-oxide / acetone / 8 h / 20 °C
With
hydrogenchloride; osmium(VIII) oxide; water; 4-methylmorpholine N-oxide; sodium hydroxide;
In
acetone; toluene;
DOI:10.1002/ejoc.201301281
