Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

Base Information

Chemical Name:Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester
CAS No.:291297-64-8
Molecular Formula:C₃₁H₃₂Cl₃NO₆S
Molecular Weight:653.023
Hs Code.:

Synonyms:Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

Suppliers and Price of Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

There total 4 articles about Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 545-06-2
trichloroacetonitrile

: 291297-63-7
Thioacetic acid S-((2S,3S,4S,5R,6S)-3,4,5-tris-benzyloxy-6-hydroxy-tetrahydro-pyran-2-ylmethyl) ester

: 291297-64-8
Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 5.5h;
DOI:10.1016/S0040-4039(00)00638-9

Reference yield:

: 78184-40-4
1-O-allyl-2,3,4-tri-O-benzyl-α-D-glucopyranoside

: 291297-64-8
Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / DMAP / pyridine / 15 h / 20 °C

2: 80 percent / PdCl₂ / methanol / 18 h / 20 °C

3: 86 percent / dimethylformamide / 3 h / 80 °C

4: 70 percent / DBU / CH₂Cl₂ / 5.5 h / 20 °C

With dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium dichloride; In pyridine; methanol; dichloromethane; N,N-dimethyl-formamide; 1: Tosylation / 2: deallylation / 3: Acylation / 4: Addition;
DOI:10.1016/S0040-4039(00)00638-9

Reference yield:

: 291297-62-6
Toluene-4-sulfonic acid (2R,3R,4S,5R,6S)-3,4,5-tris-benzyloxy-6-hydroxy-tetrahydro-pyran-2-ylmethyl ester

: 291297-64-8
Thioacetic acid S-[(2S,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(2,2,2-trichloro-acetimidoyloxy)-tetrahydro-pyran-2-ylmethyl] ester

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / dimethylformamide / 3 h / 80 °C

2: 70 percent / DBU / CH₂Cl₂ / 5.5 h / 20 °C

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; N,N-dimethyl-formamide; 1: Acylation / 2: Addition;
DOI:10.1016/S0040-4039(00)00638-9