(benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride

Base Information

• Chemical Name: (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride
• CAS No.: 83134-12-7
• Molecular Formula: C₂₉H₄₀N₆O₅*ClH
• Molecular Weight: 589.135
• Mol file: 83134-12-7.mol

Synonyms:(benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride

Chemical Property of (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride

There total 5 articles about (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C30H43N9O5*ClH → (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride (83134-12-7)

Guidance literature:

With hydrogenchloride; formaldehyd; In methanol; at 0 ℃; for 2.5h;

DOI:10.1021/jm00163a014

Reference yield:

N-benzyloxycarbonyl-L-leucyl-L-phenylalanine (6401-63-4) → (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride (83134-12-7)

Guidance literature:

Multi-step reaction with 5 steps

1: triethylamine / dimethylformamide / 0.5 h / -15 °C

2: triethylamine / dimethylformamide / 3 h / 0 °C

3: H₂, 1 M aq. HCl / 10percent Pd/C / methanol / 18 h

4: pyridine / methanol / 2 h / 0 °C

5: 37percent formalin, aq. HCl / methanol / 2.5 h / 0 °C

With pyridine; hydrogenchloride; formaldehyd; hydrogen; triethylamine; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00163a014

Reference yield:

C26H32N2O7 → (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride (83134-12-7)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine / dimethylformamide / 3 h / 0 °C

2: H₂, 1 M aq. HCl / 10percent Pd/C / methanol / 18 h

3: pyridine / methanol / 2 h / 0 °C

4: 37percent formalin, aq. HCl / methanol / 2.5 h / 0 °C

With pyridine; hydrogenchloride; formaldehyd; hydrogen; triethylamine; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00163a014

upstream raw materials:

N-benzyloxycarbonyl-L-leucyl-L-phenylalanine

(benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-N^G-nitroargininal semicarbazone