(R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate

Base Information

• Chemical Name: (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate
• CAS No.: 1462940-80-2
• Molecular Formula: C₂₀H₂₀F₄O₂
• Molecular Weight: 368.371
• Mol file: 1462940-80-2.mol

Synonyms:(R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate

Chemical Property of (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate

There total 6 articles about (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,5,6-tetrafluoro-4-methylbenzyl alcohol (79538-03-7) + (S)-(-)-3-phenyl-4-methylpentanoic acid (22573-51-9) → (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate (1462940-80-2)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In acetonitrile; at 20 ℃; for 10h;

DOI:10.1016/j.bmcl.2014.04.055

Reference yield:

2,3,5,6-tetrafluoro-4-methylbenzyl alcohol (79538-03-7) + (R)-3-phenyl-4-methylpentanoic acid (22573-54-2) → (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate (1462940-80-2)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In acetonitrile; at 20 ℃; for 10h;

DOI:10.1016/j.bmcl.2014.04.055

Reference yield:

2,3,5,6-tetrafluoro-4-methylbenzyl alcohol (79538-03-7) + 4-methyl-3-phenylpentanoic acid (51690-50-7) → (R)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate (1462940-80-2) + (S)-2,3,5,6-tetrafluoro-4-methylbenzyl 4-methyl-3-phenylpentanoate (1462940-81-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; potassium hydroxide; In ethanol; acetonitrile; at 20 ℃; for 10h; Overall yield = 52 mg;

DOI:10.1002/chem.201703274

upstream raw materials:

C₂₂H₃₁NO₃S

2,3,5,6-tetrafluoro-4-methylbenzyl alcohol

(S)-(-)-3-phenyl-4-methylpentanoic acid

(R)-3-phenyl-4-methylpentanoic acid