(E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane

Base Information

• Chemical Name: (E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane
• CAS No.: 915315-52-5
• Molecular Formula: C₂₅H₄₂OSi
• Molecular Weight: 386.693
• Mol file: 915315-52-5.mol

Synonyms:(E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane

Chemical Property of (E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane

There total 6 articles about (E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

9-(2-{2-[2-(tert-butyldimethylsilanyloxy)-ethyl]-phenyl}-ethyl)-9-borabicyclo[3.3.1]nonane + (E)-1-iodo-2,6-dimethyl-hepta-1,5-diene (71570-25-7) → (E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane (915315-52-5)

Guidance literature:

With potassium phosphate; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; N,N-dimethyl-formamide; at 60 ℃; for 3h;

DOI:10.1021/ol061962z

Reference yield:

tert-butyldimethyl-[2-(2-vinylphenyl)-ethoxy]-silane (149274-10-2) → (E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane (915315-52-5)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 1 h / Heating

2: 64 percent / K₃PO₄ / Pd(PPh₃)Cl₂ / dimethylformamide; tetrahydrofuran; H₂O / 3 h / 60 °C

With potassium phosphate; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; N,N-dimethyl-formamide; 2: Suzuki-Miyaura cross-coupling reaction;

DOI:10.1021/ol061962z

Reference yield:

tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane (915315-69-4) → (E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane (915315-52-5)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. H₂O₂ / tetrahydrofuran / 0 °C

2: tetrahydrofuran / 1 h / Heating

3: 64 percent / K₃PO₄ / Pd(PPh₃)Cl₂ / dimethylformamide; tetrahydrofuran; H₂O / 3 h / 60 °C

With potassium phosphate; dihydrogen peroxide; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; N,N-dimethyl-formamide; 3: Suzuki-Miyaura cross-coupling reaction;

DOI:10.1021/ol061962z

upstream raw materials:

(E)-1-iodo-2,6-dimethyl-hepta-1,5-diene

tert-butyldimethyl-[2-(2-vinylphenyl)-ethoxy]-silane

tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane

2,2’-(1,2-phenylene)diethanol

Downstream raw materials:

C₂₅H₃₁NO₂Se

(E)-1-(4,8-dimethylnona-3,7-dienyl)-2-vinylbenzyl

(E)-2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethanol