tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane

Base Information

• Chemical Name: tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane
• CAS No.: 915315-69-4
• Molecular Formula: C₂₂H₃₁NO₃SeSi
• Molecular Weight: 464.539
• Mol file: 915315-69-4.mol

Synonyms:tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane

Chemical Property of tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane

There total 3 articles about tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ortho-nitrophenyl selenocyanate (51694-22-5) + 2-{2-[2-(tert-butyldimethylsilanyloxy)-ethyl]-phenyl}-ethanol (497157-41-2) → tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane (915315-69-4)

Guidance literature:

With trimethylphosphane; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/ol061962z

Reference yield:

2,2’-(1,2-phenylene)diethanol (17378-99-3) → tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane (915315-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 45 percent / dimethylformamide; triethylamine / 0 - 20 °C

2: 80 percent / PMe₃ / tetrahydrofuran / 1 h / 20 °C

With trimethylphosphane; In tetrahydrofuran; triethylamine; N,N-dimethyl-formamide;

DOI:10.1021/ol061962z

Reference yield:

1,2-Phenylenediacetic acid (7500-53-0) → tert-butyldimethyl-(2-{2-[2-(2-nitrophenylselanyl)-ethyl]-phenyl}-ethoxy)-silane (915315-69-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 56 percent / LiAlH₄ / tetrahydrofuran / 0 - 20 °C

2: 45 percent / dimethylformamide; triethylamine / 0 - 20 °C

3: 80 percent / PMe₃ / tetrahydrofuran / 1 h / 20 °C

With lithium aluminium tetrahydride; trimethylphosphane; In tetrahydrofuran; triethylamine; N,N-dimethyl-formamide;

DOI:10.1021/ol061962z

upstream raw materials:

ortho-nitrophenyl selenocyanate

2-{2-[2-(tert-butyldimethylsilanyloxy)-ethyl]-phenyl}-ethanol

2,2’-(1,2-phenylene)diethanol

1,2-Phenylenediacetic acid

Downstream raw materials:

C₂₅H₃₁NO₂Se

(E)-tert-butyl-{2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethoxy}-dimethylsilane

(E)-2-[2-(4,8-dimethylnona-3,7-dienyl)-phenyl]-ethanol

(E)-1-(4,8-dimethylnona-3,7-dienyl)-2-vinylbenzyl