C₂₆H₂₃NO₆S

Base Information

• Chemical Name: C₂₆H₂₃NO₆S
• CAS No.: 647826-76-4
• Molecular Formula: C₂₆H₂₃NO₆S
• Molecular Weight: 477.538
• Mol file: 647826-76-4.mol

Synonyms:C₂₆H₂₃NO₆S

Chemical Property of C₂₆H₂₃NO₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₃NO₆S

There total 4 articles about C₂₆H₂₃NO₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

6-[2-(4,5-dimethoxy-3-oxo-1-phenylsulfanyl-1,3-dihydro-isoindol-2-yl)-ethyl]-benzo[1,3]dioxole-5-carbaldehyde (647826-75-3) → C26H23NO6S (647826-76-4)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 0 ℃;

DOI:10.1016/j.tetlet.2003.09.204

Reference yield:

thiophenol (108-98-5) → C26H23NO6S (647826-76-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: DIBAL-H / tetrahydrofuran / -78 °C

1.2: 61 percent / BF₃*OEt₂ / CH₂Cl₂

2.1: 97 percent / DDQ / CH₂Cl₂; H₂O

3.1: 65 percent / LiHMDS; HMPA / tetrahydrofuran / -78 - 0 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; diisobutylaluminium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/j.tetlet.2003.09.204

Reference yield:

4,5-dimethoxy-2-{2-[6-(4-methoxy-benzyloxymethyl)-benzo[1,3]dioxol-5-yl]-ethyl}-isoindole-1,3-dione (462085-17-2) → C26H23NO6S (647826-76-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: DIBAL-H / tetrahydrofuran / -78 °C

1.2: 61 percent / BF₃*OEt₂ / CH₂Cl₂

2.1: 97 percent / DDQ / CH₂Cl₂; H₂O

3.1: 65 percent / LiHMDS; HMPA / tetrahydrofuran / -78 - 0 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; diisobutylaluminium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; water;

DOI:10.1016/j.tetlet.2003.09.204

upstream raw materials:

6-[2-(4,5-dimethoxy-3-oxo-1-phenylsulfanyl-1,3-dihydro-isoindol-2-yl)-ethyl]-benzo[1,3]dioxole-5-carbaldehyde

thiophenol

4,5-dimethoxy-2-{2-[6-(4-methoxy-benzyloxymethyl)-benzo[1,3]dioxol-5-yl]-ethyl}-isoindole-1,3-dione

6,7-dimethoxy-2-{2-[6-(4-methoxy-benzyloxymethyl)-benzo[1,3]dioxol-5-yl]-ethyl}-3-phenylsulfanyl-2,3-dihydro-isoindol-1-one

Downstream raw materials:

C₂₆H₂₁NO₆S

12b-hydroxy-9,10-dimethoxy-5H-[1,3]dioxolo[4'',5'':4',5']benzo[1',2':4,5]azepino[2,1-a]isoindole-8,13(6H,12bH)-dione