(3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

Base Information

Chemical Name:(3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide
CAS No.:478491-04-2
Molecular Formula:C₃₀H₃₉NO₅Si
Molecular Weight:521.729
Hs Code.:

Synonyms:(3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

Suppliers and Price of (3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

There total 1 articles about (3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 478491-03-1
(S)-4-(((tert-butyldiphenylsilyl)oxy)methyl)oxetan-2-one

: 478491-04-2
(3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

Guidance literature:: Multi-step reaction with 2 steps

1.1: dimethylaluminium chloride / CH₂Cl₂; hexane / 1 h / 20 °C

1.2: 94 percent / CH₂Cl₂ / 2 h / 20 °C

2.1: 77 percent / trifluoromethanesulfonic acid / diethyl ether / 0.5 h / 20 °C

With trifluorormethanesulfonic acid; dimethylaluminum chloride; In diethyl ether; hexane; dichloromethane;
DOI:10.1021/ja028019k

Reference yield:

: 478491-04-2
(3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

: 478491-02-0
(4E)(2S)-(4-methoxybenzyloxy)-6-(triphenylmethyloxy)hex-4-en-1-al

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / DIBAL-H / hexane; tetrahydrofuran / 0.75 h / -78 °C

2: 95 percent / KHMDS / tetrahydrofuran; toluene / 1 h / 20 °C

3: 89 percent / DIBAL-H / tetrahydrofuran; hexane / 1.5 h / -78 - 0 °C

4: 92 percent / 2,6-lutidine; tetra-n-butylammonium iodide / CH₂Cl₂ / 5.5 h / 20 °C

5: 99 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C

6: 94 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / 20 °C

With 2,6-dimethylpyridine; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; potassium hexamethylsilazane; diisobutylaluminium hydride; Dess-Martin periodane; In tetrahydrofuran; hexane; dichloromethane; toluene;
DOI:10.1021/ja028019k

Reference yield:

: 478491-04-2
(3S)-4-(tert-butyldiphenylsilanyloxy)-N-methoxy-(4-methoxybenzyloxy)-N-methylbutyramide

: 478491-19-9
(4E)(2S)-(4-methoxybenzyloxy)-6-(triphenylmethyloxy)hex-4-en-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1: 80 percent / DIBAL-H / hexane; tetrahydrofuran / 0.75 h / -78 °C

2: 95 percent / KHMDS / tetrahydrofuran; toluene / 1 h / 20 °C

3: 89 percent / DIBAL-H / tetrahydrofuran; hexane / 1.5 h / -78 - 0 °C

4: 92 percent / 2,6-lutidine; tetra-n-butylammonium iodide / CH₂Cl₂ / 5.5 h / 20 °C

5: 99 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C

With 2,6-dimethylpyridine; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; potassium hexamethylsilazane; diisobutylaluminium hydride; In tetrahydrofuran; hexane; dichloromethane; toluene;
DOI:10.1021/ja028019k