(Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

Base Information

Chemical Name:(Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate
CAS No.:872025-60-0
Molecular Formula:C₂₈H₃₅N₆O₅PSi
Molecular Weight:594.682
Hs Code.:

Synonyms:(Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

Suppliers and Price of (Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

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Technology Process of (Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

There total 1 articles about (Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 872025-03-1
(S_P)-8-bromoadenosine-2'-O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

: 960-16-7
tributylphenylstannane

: 872025-60-0
(Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

Guidance literature:: palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; at 50 - 135 ℃; for 7h;

Reference yield:

: 872025-60-0
(Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate

: C₂₂H₃₀N₅O₅PSSi

Guidance literature:: (Sp)-8-phenyladenosine-2'O-(tert-butyldimethylsilyl)-3',5'-cyclic N-phenylphosphoramidate; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h;

With carbon disulfide; In tetrahydrofuran; at 20 ℃; for 3h;

With hydrogenchloride; water; at 0 ℃;