N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Base Information

Chemical Name:N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine
CAS No.:1555938-57-2
Molecular Formula:C₄₂H₃₉N₅O₄
Molecular Weight:677.803
Hs Code.:

N<sub>1</sub>,N<sub>2</sub>-bis(benzyloxycarbonyl)-N<sub>1</sub>-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Synonyms:N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Suppliers and Price of N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

There total 3 articles about N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 172499-78-4
3-[N-Triphenylmethyl-imidazol-2-yl]-propan-1-ol

: 10065-79-9
N₁,N₂-bis(benzyloxycarbonyl)guanidine

: 1555938-57-2
N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1039/c3md00245d

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 1555938-57-2
N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / dichloromethane; water / 20 h / 0 °C

2: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

With di-isopropyl azodicarboxylate; triphenylphosphine; sodium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1039/c3md00245d

Reference yield:

: 23593-68-2
2-methyl-1-tritylimidazole

: 1555938-57-2
N₁,N₂-bis(benzyloxycarbonyl)-N₁-[3-(1-trityl-1H-imidazol-2-yl)propyl]guanidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: hexane; tetrahydrofuran / 1 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; hexane;
DOI:10.1039/c3md00245d