C₂₁H₂₅F₃N₂O₂

Base Information

Chemical Name:C₂₁H₂₅F₃N₂O₂
CAS No.:1403947-78-3
Molecular Formula:C₂₁H₂₅F₃N₂O₂
Molecular Weight:394.437
Hs Code.:

C<sub>21</sub>H<sub>25</sub>F<sub>3</sub>N<sub>2</sub>O<sub>2</sub>

Synonyms:C₂₁H₂₅F₃N₂O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₁H₂₅F₃N₂O₂

Chemical Property:

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Technology Process of C₂₁H₂₅F₃N₂O₂

There total 7 articles about C₂₁H₂₅F₃N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1403947-76-1
C₂₂H₂₈F₃N₃O₃

: 75-16-1
methylmagnesium bromide

: 1403947-78-3
C₂₁H₂₅F₃N₂O₂

Guidance literature:: C₂₂H₂₈F₃N₃O₃; methylmagnesium bromide; In diethyl ether; toluene; at 0 - 20 ℃; for 3h;

With water; ammonium chloride; In diethyl ether; toluene;

Reference yield:

: 5469-26-1
1-Bromopinacolon

: 1403947-78-3
C₂₁H₂₅F₃N₂O₂

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C

1.2: 20 °C

2.1: sodium acetate / ethanol / 4 h / 80 °C

3.1: hydrogen / palladium on activated charcoal / ethyl acetate; methanol / 20 °C

4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; pyridine / 20 °C

5.1: water; lithium hydroxide / tetrahydrofuran / 20 °C

5.2: pH 3 - 4

6.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; pyridine / 20 °C

7.1: toluene; diethyl ether / 3 h / 0 - 20 °C

With pyridine; water; hydrogen; sodium acetate; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; ethanol; ethyl acetate; toluene;

Reference yield:

: 1403947-70-5
C₂₂H₂₉NO₄

: 1403947-78-3
C₂₁H₂₅F₃N₂O₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrogen / palladium on activated charcoal / ethyl acetate; methanol / 20 °C

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; pyridine / 20 °C

3.1: water; lithium hydroxide / tetrahydrofuran / 20 °C

3.2: pH 3 - 4

4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; pyridine / 20 °C

5.1: toluene; diethyl ether / 3 h / 0 - 20 °C

With pyridine; water; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; ethyl acetate; toluene;