2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid

Base Information

• Chemical Name: 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid
• CAS No.: 118387-93-2
• Molecular Formula: C₂₃H₂₉NO₅S
• Molecular Weight: 431.553

Synonyms:2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid

Chemical Property of 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid

There total 4 articles about 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propylsulfanyl)-3-phenyl-propionic acid (84765-20-8,84765-22-0,118387-92-1) → 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid (118387-93-2)

Guidance literature:

With sodium periodate; In methanol; for 2h; Ambient temperature;

DOI:10.1021/jm00164a058

Reference yield:

(2S)-2-benzylazacyclopropane (73058-30-7) → 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid (118387-93-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 100 percent / H₂S / ethanol / from -78 deg C to room temp.

2: 82 percent / liq. NH₃ / overnight

3: Et₃N / CH₂Cl₂ / 0 °C

4: trifluoroacetic acid

5: 0.5 M NaIO₄ / methanol / 2 h / Ambient temperature

With sodium periodate; hydrogen sulfide; ammonia; triethylamine; trifluoroacetic acid; In methanol; ethanol; dichloromethane;

DOI:10.1021/jm00164a058

Reference yield:

(S)-2-amino-3-phenyl-1-propanethiol (116264-32-5) → 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid (118387-93-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 82 percent / liq. NH₃ / overnight

2: Et₃N / CH₂Cl₂ / 0 °C

3: trifluoroacetic acid

4: 0.5 M NaIO₄ / methanol / 2 h / Ambient temperature

With sodium periodate; ammonia; triethylamine; trifluoroacetic acid; In methanol; dichloromethane;

DOI:10.1021/jm00164a058

upstream raw materials:

2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propylsulfanyl)-3-phenyl-propionic acid

(2S)-2-benzylazacyclopropane

(S)-2-amino-3-phenyl-1-propanethiol

2-((S)-2-Amino-3-phenyl-propylsulfanyl)-3-phenyl-propionic acid tert-butyl ester

Downstream raw materials:

((S)-1-Benzyl-2-{1-[(S)-1-((S)-2-{(S)-1-[(S)-1-((S)-2-benzylcarbamoyl-1-hydroxy-ethyl)-3-methyl-butylcarbamoyl]-ethylcarbamoyl}-1-hydroxy-ethyl)-3-methyl-butylcarbamoyl]-2-phenyl-ethanesulfinyl}-ethyl)-carbamic acid tert-butyl ester

[(S)-1-Benzyl-2-(1-{(S)-1-[(S)-2-((S)-1-benzylcarbamoyl-3-methyl-butylcarbamoyl)-1-hydroxy-ethyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethanesulfinyl)-ethyl]-carbamic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 118387-93-2 2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propane-1-sulfinyl)-3-phenyl-propionic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send