(2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Base Information

Chemical Name:(2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester
CAS No.:479673-56-8
Molecular Formula:C₅₆H₇₆O₉
Molecular Weight:893.214
Hs Code.:

(2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Synonyms:(2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Suppliers and Price of (2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

There total 23 articles about (2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 479673-34-2
(6R, [7R,] [12S,] 13S, [14S,] [19R,] [20R,] [21R,] 22S)-21-(TERT-BUTYLDIMETHYLSILANYLOXY)-7,13, [19-TRIS-(4-METHOXYBENZYLOXY)-6,] 12,14, 20,22-pentamethylhexacosa-2, 4,10, 15,23, 25-hexaenoic acid methyl ester

: 479673-56-8
(2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; methanol; water;
DOI:10.1021/ol026942l

Reference yield:

: 154919-93-4
(S)-4-Benzyl-3-[(2S,3R)-6-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2-methyl-hexanoyl]-oxazolidin-2-one

: 479673-56-8
(2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Guidance literature:: Multi-step reaction with 14 steps

1.1: LiBH₄

1.2: PPTS

2.1: 92 percent / DIBAL

3.1: Dess-Martin periodinane

4.1: NaH

5.1: 84 percent / HF*pyridine

6.1: 72 percent / Dess-Martin periodinane

7.1: 74 percent / NaHMDS

8.1: 68 percent / NaCNBH₃; TMSCl

9.1: 89 percent / Dess-Martin periodinane

10.1: 48 percent / NaHMDS

11.1: 77 percent / DIBAL

12.1: Dess-Martin periodinane

13.1: KHMDS; 18-crown-6

14.1: 63 percent / HCl / methanol; H₂O; tetrahydrofuran

With hydrogenchloride; lithium borohydride; chloro-trimethyl-silane; 18-crown-6 ether; sodium hexamethyldisilazane; potassium hexamethylsilazane; sodium hydride; diisobutylaluminium hydride; sodium cyanoborohydride; Dess-Martin periodane; pyridine hydrogenfluoride; In tetrahydrofuran; methanol; water; 3.1: Dess-Martin oxidation / 4.1: Wittig-Horner reaction / 6.1: Dess-Martin oxidation / 7.1: Wittig reaction / 9.1: Dess-Martin oxidation / 10.1: Wittig reaction / 12.1: Dess-Martin oxidation;
DOI:10.1021/ol026942l

Reference yield:

: 479673-40-0
(2S,3R)-6-(tert-butyldimethylsilanyloxy)-3-(4-methoxybenzyloxy)-2-methylhexanal

: 479673-56-8
(2Z,4E,10Z,15Z,23Z)-(6R,7R,12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-7,13,19-tris-(4-methoxy-benzyloxy)-6,12,14,20,22-pentamethyl-hexacosa-2,4,10,15,23,25-hexaenoic acid methyl ester

Guidance literature:: Multi-step reaction with 11 steps

1: NaH

2: 84 percent / HF*pyridine

3: 72 percent / Dess-Martin periodinane

4: 74 percent / NaHMDS

5: 68 percent / NaCNBH₃; TMSCl

6: 89 percent / Dess-Martin periodinane

7: 48 percent / NaHMDS

8: 77 percent / DIBAL

9: Dess-Martin periodinane

10: KHMDS; 18-crown-6

11: 63 percent / HCl / methanol; H₂O; tetrahydrofuran

With hydrogenchloride; chloro-trimethyl-silane; 18-crown-6 ether; sodium hexamethyldisilazane; potassium hexamethylsilazane; sodium hydride; diisobutylaluminium hydride; sodium cyanoborohydride; Dess-Martin periodane; pyridine hydrogenfluoride; In tetrahydrofuran; methanol; water; 1: Wittig-Horner reaction / 3: Dess-Martin oxidation / 4: Wittig reaction / 6: Dess-Martin oxidation / 7: Wittig reaction / 9: Dess-Martin oxidation;
DOI:10.1021/ol026942l