methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside

Base Information

• Chemical Name: methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside
• CAS No.: 214068-24-3
• Molecular Formula: C₂₉H₃₄O₇
• Molecular Weight: 494.585
• Mol file: 214068-24-3.mol

Synonyms:methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside

Chemical Property of methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside

There total 9 articles about methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-6-O-trityl-α-D-glucopyranoside → methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside (214068-24-3)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; for 1h; Yield given; Ambient temperature;

DOI:10.1021/jo980501r

Reference yield:

methyl 2-O-(p-methoxybenzyl)-6-O-trityl-α-D-glucopyranoside (214068-17-4) → methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside (214068-24-3)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 2 h / Ambient temperature

2: p-TsOH monohydrate / methanol / 1 h / Ambient temperature

With sodium hydride; toluene-4-sulfonic acid; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jo980501r

Reference yield:

benzyl bromide (100-39-0) → methyl 3,4-di-O-benzyl-2-O-(p-methoxybenzyl)-α-D-glucopyranoside (214068-24-3)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH / dimethylformamide / 2 h / Ambient temperature

2: p-TsOH monohydrate / methanol / 1 h / Ambient temperature

With sodium hydride; toluene-4-sulfonic acid; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jo980501r

upstream raw materials:

benzyl bromide

methyl 2-O-(p-methoxybenzyl)-α-D-glucopyranoside

methyl 2-O-(p-methoxybenzyl)-4,6-O-(p-methoxybenzylidene)-α-D-glucopyranoside

methyl 2-O-(p-methoxybenzyl)-6-O-trityl-α-D-glucopyranoside

Downstream raw materials:

Acetic acid (1R,3S,4R,5S,6R)-3,4-bis-benzyloxy-6-hydroxy-5-(4-methoxy-benzyloxy)-2-oxo-cyclohexyl ester

methyl (Z)-3,4-O-dibenzyl-2-O-(p-methoxybenzyl)-6-O-acetyl-α-D-glucos-5-enopyranoside

(1R,2R,3R,4R,5S,6S)-4,5-Bis-benzyloxy-2,6-bis-benzyloxymethoxy-cyclohexane-1,3-diol

Phosphoric acid benzyl ester (1R,2R,3S,4R,5R,6R)-3,4-bis-benzyloxy-2,6-bis-benzyloxymethoxy-5-hydroxy-cyclohexyl ester (S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester