(Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide

Base Information

• Chemical Name: (Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide
• CAS No.: 1450754-01-4
• Molecular Formula: C₁₅H₂₀N₂O₂
• Molecular Weight: 260.336
• Mol file: 1450754-01-4.mol

Synonyms:(Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide

Chemical Property of (Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide

There total 3 articles about (Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N-tert-butylmethacrylamide (6554-73-0) + 3-phenyl-5H-1,4,2-dioxazol-5-one (19226-36-9) → (Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide (1450754-01-4)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) triflimide; In 1,2-dichloro-ethane; at 50 ℃; for 12h;

DOI:10.1002/chem.201702397

Reference yield: 48.0%

N-tert-butylmethacrylamide (6554-73-0) + benzoyl azide (582-61-6) → (Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide (1450754-01-4)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) triflimide; In 1,2-dichloro-ethane; at 50 ℃; for 24h;

DOI:10.1021/ja406383h

Reference yield:

benzoyl chloride (98-88-4) → (Z)-N-[3-(tert-butylamino)-2-methyl-3-oxoprop-1-enyl]benzamide (1450754-01-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / water; acetone / 11 h / 0 - 20 °C

2: bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) triflimide / 1,2-dichloro-ethane / 24 h / 50 °C

With sodium azide; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; silver(I) triflimide; In water; 1,2-dichloro-ethane; acetone;

DOI:10.1021/ja406383h

upstream raw materials:

N-tert-butylmethacrylamide

benzoyl azide

benzoyl chloride

3-phenyl-5H-1,4,2-dioxazol-5-one