Technology Process of C35H41FN6O5S
There total 11 articles about C35H41FN6O5S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
tert-butyl 9-(4,6-dimethylpyrimidin-2-yl)-5-oxo-1,4,9-triazaspiro[5.5]undecane-1-carboxylate;
With
tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran;
at 0 ℃;
for 0.25h;
3-Bromomethyl-5-fluoro-1-(toluene-4-sulfonyl)-1H-indole;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium acetate; acetic acid; sodium tris(acetoxy)borohydride / dichloromethane / 0.67 h / Inert atmosphere
1.2: 0.08 h / 0 °C
2.1: trifluoroacetic acid / dichloromethane / 1.5 h / 20 °C / Inert atmosphere
2.2: 22 h / 0 °C / Reflux
3.1: N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane / 112 h / 20 °C
4.1: hydrogen / 10 wt% Pd(OH)2 on carbon / tetrahydrofuran; methanol / 20 °C / 37503.8 Torr
5.1: N-ethyl-N,N-diisopropylamine / ethanol / 1 h / 120 °C / microwave irradiation; sealed tube
6.1: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran / 0.25 h / 0 °C
6.2: 0.5 h / 0 - 20 °C
With
hydrogen; sodium acetate; sodium tris(acetoxy)borohydride; sodium hydride; acetic acid; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
10 wt% Pd(OH)2 on carbon; tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrahydrofuran / 0.58 h / -10 - 0 °C
2.1: bromine / dichloromethane / 3.25 h / 0 - 20 °C / Inert atmosphere
3.1: sodium hydride / tetra-(n-butyl)ammonium iodide / tetrahydrofuran / 0.25 h / 0 °C
3.2: 0.5 h / 0 - 20 °C
With
bromine; sodium hydride;
tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran; dichloromethane;