pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate

Base Information

• Chemical Name: pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate
• CAS No.: 130831-96-8
• Molecular Formula: C₁₈H₁₂F₅NO₄
• Molecular Weight: 401.29

Synonyms:pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate

Chemical Property of pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate

Chemical Property:

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Technology Process of pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate

There total 1 articles about pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,3,4,5,6-pentafluorophenol (771-61-9) + (benzyloxycarbonylamino)cyclopropanecarboxylic acid (84677-06-5) → pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate (130831-96-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In ethyl acetate; at 0 ℃; for 1h;

Reference yield: 92.0%

L-arginine (74-79-3,25212-18-4) + pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate (130831-96-8) → benzyloxycarbonyl-1-aminocyclopropane-1-carbonyl-arginine (130831-97-9)

Guidance literature:

In 1,4-dioxane; water; for 2h; Ambient temperature;

Reference yield:

pentafluorophenyl benzyloxycarbonyl-1-aminocyclopropane-1-carboxylate (130831-96-8) + Nε-benzyloxycarbonyllysyl-1-aminocyclopropane-1-carbonyl-arginine → benzyloxycarbonyl-1-aminocyclopropane-1-carbonyl-Nε-benzyloxycarbonyllysyl-1-aminocyclopropane-1-carbonyl-arginine (130832-00-7)

Guidance literature:

In 1,4-dioxane; water; for 2h; Yield given; Ambient temperature;

upstream raw materials:

2,3,4,5,6-pentafluorophenol

(benzyloxycarbonylamino)cyclopropanecarboxylic acid

Downstream raw materials:

benzyloxycarbonyl-1-aminocyclopropane-1-carbonyl-arginine

benzyloxycarbonyl-1-aminocyclopropane-1-carbonyl-N^ε-benzyloxycarbonyllysyl-1-aminocyclopropane-1-carbonyl-arginine

benzylcarbonyl-1-aminocyclopropane-1-carbonyl-N^ε-benzyloxycarbonyllysyl-prolyl-arginine

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