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Sesbanimide

Base Information Edit
  • Chemical Name:Sesbanimide
  • CAS No.:85719-78-4
  • Molecular Formula:C15H21NO7
  • Molecular Weight:327.334
  • Hs Code.:
  • Mol file:85719-78-4.mol
Sesbanimide

Synonyms:

Suppliers and Price of Sesbanimide
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Sesbanimide A
  • 1mg
  • $ 1359.00
  • TRC
  • SesbanimideA
  • 1mg
  • $ 720.00
Total 0 raw suppliers
Chemical Property of Sesbanimide Edit
Chemical Property:
  • Vapor Pressure:7.31E-17mmHg at 25°C 
  • Boiling Point:599.3°C at 760 mmHg 
  • Flash Point:316.3°C 
  • PSA:117.81000 
  • Density:1.4g/cm3 
  • LogP:-0.67140 
Purity/Quality:

Sesbanimide A *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses Sesbanimide A is an antiproliferative antitumor alkaloid initially extracted from the seeds of seeds of the leguminous plants Sesbania drummondii and Sesbania punicea.
Technology Process of Sesbanimide

There total 138 articles about Sesbanimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Refernces Edit

EFFICIENT SYNTHESIS AND ANTITUMOR ACTIVITY OF AN ENANTIOMERIC PAIR OF THE SESBANIMIDE AB-RING SYSTEMS

10.1016/S0040-4039(00)98773-2

This study focused on the synthesis and antitumor activity of the AB ring system enantiomers of Sesbanimide A, a potent antitumor alkaloid isolated from the seeds of Sesbania drummondii and S. punices. The researchers efficiently synthesized the fully unprotected AB ring system enantiomers from readily available D- and L-xylose. The synthetic route involved several steps, including hydroxyl protection, ring opening and carbon chain extension, construction of the dioxane ring, Michael addition, demethoxycarbonylation, and catalytic hydrogenation. The synthesized compounds were then tested for in vitro antitumor activity against P388 murine leukemia, and the results showed that the AB ring system itself contributed little to the cytotoxicity of Sesbanimide A, indicating that the significant antitumor activity of Sesbanimide A mainly comes from its characteristic C ring.

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