
Tetrahedron Letters p. 4639 - 4642 (1985)
Update date:2022-09-26
Topics:
Matsuda, Fuyuhiko
Kawasaki, Motojio
Terashima, Shiro
An enantiomeric pair of the fully unprotected AB-ring systems of sesbanimide A (1), a potent antitumor alkaloid, was efficiently synthesized from readily available D- and L-xylose.Examination on their in vitro antitumor activity clearly disclosed that the AB-ring system only made a small contribution to the notable cytotoxicity of 1.
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