2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone

Base Information

• Chemical Name: 2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone
• CAS No.: 865712-71-6
• Molecular Formula: C₁₈H₂₂ClNO₂
• Molecular Weight: 319.831
• Mol file: 865712-71-6.mol

Synonyms:2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone

Chemical Property of 2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone

There total 1 articles about 2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-cyclohexylmethyl-7-methoxyindole (639068-82-9) + chloroacetyl chloride (79-04-9) → 2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone (865712-71-6)

Guidance literature:

With pyridine; In toluene; at 20 - 55 ℃; for 0.5h;

Reference yield:

2-chloro-1-[1-(cyclohexyl)methyl-7-methoxy-1H-indol-3-yl] ethanone (865712-71-6) + 2,2-dimethyl-propionic acid thiocarbamoylmethyl ester (175204-79-2) → 1-(cyclohexyl)methyl-7-methoxy-3-{2-[(tertbutylcarbonyloxy)methyl]thiazol-4-yl}-1H-indole (865712-72-7)

Guidance literature:

In ethanol; at 150 ℃; for 0.166667h; Irradiation;

upstream raw materials:

N-cyclohexylmethyl-7-methoxyindole

chloroacetyl chloride

Downstream raw materials:

1-(cyclohexyl)methyl-7-methoxy-3-{2-[(tertbutylcarbonyloxy)methyl]thiazol-4-yl}-1H-indole