2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

Base Information Edit

Chemical Name:2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone
CAS No.:294182-06-2
Molecular Formula:C₁₃H₆BrF₄NO
Molecular Weight:348.094
Hs Code.:
Mol file:294182-06-2.mol

Synonyms:2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

Suppliers and Price of 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone Edit

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

There total 8 articles about 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.4%

: 348-57-2
2,4-difluorobromobenzene

: 294181-95-6
2-(5-bromopyridine-2-yl)-2,2-difluoroacetic acid ethyl ester

: 294182-06-2
2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

Guidance literature:: 2,4-difluorobromobenzene; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 0.5h;

2-(5-bromopyridine-2-yl)-2,2-difluoroacetic acid ethyl ester; In diethyl ether; hexane; at -78 - 20 ℃; for 2h;
DOI:10.1248/cpb.48.982

Reference yield: 32.4%

: 348-57-2
2,4-difluorobromobenzene

: 294181-95-6
2-(5-bromopyridine-2-yl)-2,2-difluoroacetic acid ethyl ester

: 2-(5-bromo-2-pyridyl)-2,2-difluoro-1-(2,6-difluorophenyl)ethanone

: 294182-06-2
2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

Guidance literature:: 2,4-difluorobromobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

2-(5-bromopyridine-2-yl)-2,2-difluoroacetic acid ethyl ester; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2h;
DOI:10.1248/cpb.48.982

Reference yield:

: 348-57-2
2,4-difluorobromobenzene

: 2-(5-bromopyridin-2-yl)-2,2-difluoro-1-morpholinoethanone

: 294182-06-2
2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone

Guidance literature:: 2,4-difluorobromobenzene; With magnesium; In tetrahydrofuran; at 20 - 44 ℃;

2-(5-bromopyridin-2-yl)-2,2-difluoro-1-morpholinoethanone; In tetrahydrofuran; at -5 - 0 ℃;