N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole

Base Information

• Chemical Name: N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole
• CAS No.: 120927-75-5
• Molecular Formula: C₃₃H₃₉NO₅Si
• Molecular Weight: 557.762

Synonyms:N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole

Chemical Property of N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole

There total 4 articles about N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3-O-isopropylidene-5-O-methyl-D-ribono-1,4-lactone (71671-16-4) → N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole (120927-75-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) Me₂AlCl / 1.) CH₂Cl₂, hexane, RT, 15 min, 2.) CH₂CL₂, phosphate buffer 2.5 h

2: imidazole, 4-(dimethylamino)pyridine / dimethylformamide / 40 h

3: 1.) ozone, 2.) Me₂S, oxalic acid / 1.) CH₂Cl₂, -78 deg C, 2.) reflux, 48 h

With 1H-imidazole; dmap; dimethylsulfide; dimethylaluminum chloride; oxalic acid; ozone; In N,N-dimethyl-formamide;

DOI:10.1021/jo00275a015

Reference yield:

2-allyl-phenylamine (32704-22-6) → N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole (120927-75-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) Me₂AlCl / 1.) CH₂Cl₂, hexane, RT, 15 min, 2.) CH₂CL₂, phosphate buffer 2.5 h

2: imidazole, 4-(dimethylamino)pyridine / dimethylformamide / 40 h

3: 1.) ozone, 2.) Me₂S, oxalic acid / 1.) CH₂Cl₂, -78 deg C, 2.) reflux, 48 h

With 1H-imidazole; dmap; dimethylsulfide; dimethylaluminum chloride; oxalic acid; ozone; In N,N-dimethyl-formamide;

DOI:10.1021/jo00275a015

Reference yield:

2-(2-propenyl)-1-(2,3-O-isopropylidene-5-O-methyl-D-ribone)anilide (120927-74-4) → N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole (120927-75-5)

Guidance literature:

Multi-step reaction with 2 steps

1: imidazole, 4-(dimethylamino)pyridine / dimethylformamide / 40 h

2: 1.) ozone, 2.) Me₂S, oxalic acid / 1.) CH₂Cl₂, -78 deg C, 2.) reflux, 48 h

With 1H-imidazole; dmap; dimethylsulfide; oxalic acid; ozone; In N,N-dimethyl-formamide;

DOI:10.1021/jo00275a015

upstream raw materials:

(4R,5R)-2,2-dimethyl-5-<2-methoxy-1(R)-<(tert-butyldiphenylsilyl)oxy>ethyl>-N-<2-(2-propenyl)phenyl>-1,3-dioxolane-4-carboxamide

2,3-O-isopropylidene-5-O-methyl-D-ribono-1,4-lactone

2-allyl-phenylamine

2-(2-propenyl)-1-(2,3-O-isopropylidene-5-O-methyl-D-ribone)anilide

Downstream raw materials:

4-O-(tert-Butyldiphenylsilyl)-2,3-O-isopropylidene-5-O-methyl-D-ribonic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 120927-75-5 N-<2,3-O-isopropylidene-5-O-methyl-4-O-(tert-butyldiphenylsilyl)-D-ribonyl>indole

Send

Send

Metric Ton KG G Pound L ML

Send

Send