4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione

Base Information

• Chemical Name: 4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione
• CAS No.: 854036-02-5
• Molecular Formula: C₁₀H₁₈N₄S
• Molecular Weight: 226.346
• Mol file: 854036-02-5.mol

Synonyms:4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione

Chemical Property of 4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione

There total 1 articles about 4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

cyclohexanepropionic acid (701-97-3) + Thiocarbohydrazide (2231-57-4) → 4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione (854036-02-5)

Guidance literature:

at 160 - 170 ℃; for 2h;

DOI:10.1080/00397911.2010.501475

Reference yield: 75.0%

4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione (854036-02-5) + 4-Nitrophenacyl bromide (99-81-0) → 3-[2-cyclohexylethyl]-6-(4-nitrophenyl)-7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine (1346462-17-6)

Guidance literature:

In ethanol; for 1h; Reflux;

DOI:10.1016/j.ejmech.2011.09.020

Reference yield: 75.0%

4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione (854036-02-5) + N-(6-chlorobenzothiazol-2-yl)-2-chloroacetamide (3174-13-8) → 4-amino-5-(2-cyclohexylethyl)-3-[N-(6-chlorobenzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole (1313371-63-9)

Guidance literature:

4-amino-5-(2-cyclohexylethyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione; N-(6-chlorobenzothiazol-2-yl)-2-chloroacetamide; With potassium carbonate; In toluene; at 20 ℃;

With triethylamine; In toluene; at 20 ℃;

DOI:10.1080/00397911.2010.501475

upstream raw materials:

cyclohexanepropionic acid

Thiocarbohydrazide

Downstream raw materials:

4-amino-5-(2-cyclohexylethyl)-3-[N-(6-methylbenzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole

4-amino-5-(2-cyclohexylethyl)-3-[N-(6-ethoxylbenzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole

4-amino-5-(2-cyclohexylethyl)-3-[N-(benzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole

4-amino-5-(2-cyclohexylethyl)-3-[N-(6-chlorobenzothiazole-2-yl)acetamido]thio-4H-1,2,4-triazole