Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat]

Base Information

• Chemical Name: Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat]
• CAS No.: 374752-67-7
• Molecular Formula: C₁₂H₁₆N₂O₅
• Molecular Weight: 268.269
• Mol file: 374752-67-7.mol

Synonyms:Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat]

Chemical Property of Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat]

There total 1 articles about Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

diazoacetic acid ethyl ester (623-73-4) + 5,5-dimethyl-cyclohexane-1,2,3-trione (32999-99-8) → Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat] (374752-67-7)

Guidance literature:

In diethyl ether; at 0 ℃; for 1.5h;

DOI:10.1002/1522-2675(20010711)84:7<2071::AID-HLCA2071>3.0.CO;2-D

Reference yield:

Ethyl-[2-diazo-2-(1-hydroxy-4,4-dimethyl-2,6-dioxocyclohexyl)acetat] (374752-67-7) → 5,5-Dimethyl-3-oxocyclohex-1-en-1-carbonsaeure (28312-42-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 30 percent / HCl-gas / diethyl ether / 0 - 4 °C

2: 38 percent / 20 percent H₂SO₄ / dioxane / 2 h / Heating

With hydrogenchloride; sulfuric acid; In 1,4-dioxane; diethyl ether;

DOI:10.1002/1522-2675(20010711)84:7<2071::AID-HLCA2071>3.0.CO;2-D

upstream raw materials:

diazoacetic acid ethyl ester

5,5-dimethyl-cyclohexane-1,2,3-trione

Downstream raw materials:

5,5-Dimethyl-3-oxocyclohex-1-en-1-carbonsaeure