1-(3,4-Dimethoxyphenyl)propan-2-ol

Base Information

• Chemical Name: 1-(3,4-Dimethoxyphenyl)propan-2-ol
• CAS No.: 19578-92-8
• Molecular Formula: C11H16 O3
• Molecular Weight: 196.246
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID80936454
• Nikkaji Number: J35.477E
• Mol file: 19578-92-8.mol

Synonyms:1-(3,4-dimethoxyphenyl)propan-2-ol;19578-92-8;1-(3,4-Dimethoxyphenyl)-2-propanol;BRN 2049658;2-Propanol, l-(3,4-dimethoxyphenyl)-;4-06-00-07403 (Beilstein Handbook Reference);SCHEMBL4598867;DTXSID80936454;AKOS009541210;SB45676;CS-16172;LS-122162;CS-0092697;FT-0630061;FT-0771586;Benzeneethanol, 3,4-dimethoxy-.alpha.-methyl-;D75342;EN300-1856961;Phenethyl alcohol, 3,4-dimethoxy-.alpha.-methyl-

Chemical Property of 1-(3,4-Dimethoxyphenyl)propan-2-ol

Chemical Property:

• Vapor Pressure: 0.000642mmHg at 25°C
• Boiling Point: 296.6°Cat760mmHg
• Flash Point: 133.2°C
• PSA: 38.69000
• Density: 1.062g/cm³
• LogP: 1.62710
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 196.109944368
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

97% ^*data from raw suppliers

1-(3,4-Dimethoxyphenyl)propan-2-ol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC(=C(C=C1)OC)OC)O

Technology Process of 1-(3,4-Dimethoxyphenyl)propan-2-ol

There total 7 articles about 1-(3,4-Dimethoxyphenyl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,4-dimethoxyphenylacetone (776-99-8) → 1-(3,4-dimethoxyphenyl)-2-propanol (19578-92-8,161121-03-5)

Guidance literature:

With zirconium dioxide hydrate; isopropyl alcohol; at 130 ℃; for 0.666667h;

DOI:10.1021/ol400856g

Reference yield: 78.03%

1,2-dimethoxy-4-(2-propenyl)benzene (93-15-2) → 1-(3,4-dimethoxyphenyl)-2-propanol (19578-92-8,161121-03-5)

Guidance literature:

1,2-dimethoxy-4-(2-propenyl)benzene; With mercury(II) diacetate;

With sodium tetrahydroborate;

DOI:10.1515/chem-2019-0047

Reference yield:

1,2-dimethoxy-4-(E)-propenylbenzene (6379-72-2) → 1-(3,4-dimethoxyphenyl)-2-propanol (19578-92-8,161121-03-5) + (R)-1-(3,4-dimethoxyphenyl)-1-propanol + (S)-1-(3,4-dimethoxyphenyl)-1-propanol

Guidance literature:

1,2-dimethoxy-4-(E)-propenylbenzene; With trimethylsilyl trifluoromethanesulfonate; benzo[1,3,2]dioxaborole; acethylacetonato(1,5-cyclooctadiene)rhodium(I); (R)-diphenyl[1-(2-phenylquinazolin-4-yl)(2-naphthyl)]phosphine; In tetrahydrofuran; at 25 ℃; for 2h;

With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; at 20 ℃; for 1h; Further stages. Title compound not separated from byproducts.;

DOI:10.1039/b004014m

upstream raw materials:

3,4-dimethoxyphenylacetone

1,2-dimethoxy-4-(2-propenyl)benzene

1,2-dimethoxybenzene

propene

Downstream raw materials:

(4,5-dimethoxy-2-nitro-phenyl)-acetone

2-Chloro-1-(3,4-dimethoxyphenyl)propane

1-(4-fluorophenyl)-6,7-dimethoxy-3-methylisochroman

1-(4-chlorophenyl)-6,7-dimethoxy-3-methylisochroman