3-[2-[(4-fluorophenyl)methylidene]hydrazinyl]-1H-quinoxalin-2-one

Base Information

Chemical Name:3-[2-[(4-fluorophenyl)methylidene]hydrazinyl]-1H-quinoxalin-2-one
CAS No.:129227-27-6
Molecular Formula:C₁₅H₁₁FN₄O
Molecular Weight:282.277
Hs Code.:
DSSTox Substance ID:DTXSID401166295
Mol file:129227-27-6.mol

Synonyms:129227-27-6;3-[2-[(4-fluorophenyl)methylidene]hydrazinyl]-1H-quinoxalin-2-one;3-{2-[(4-fluorophenyl)methylidene]hydrazin-1-yl}-1,2-dihydroquinoxalin-2-one;DTXSID401166295;AKOS030244651;4-Fluorobenzaldehyde 2-(3,4-dihydro-3-oxo-2-quinoxalinyl)hydrazone

Suppliers and Price of 3-[2-[(4-fluorophenyl)methylidene]hydrazinyl]-1H-quinoxalin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Fluorobenzenecarbaldehyde N-(3-oxo-3,4-dihydro-2-quinoxalinyl)hydrazone
5g
$ 7343.00

Matrix Scientific
4-Fluorobenzenecarbaldehyde N-(3-oxo-3,4-dihydro-2-quinoxalinyl)hydrazone
1g
$ 1836.00

Matrix Scientific
4-Fluorobenzenecarbaldehyde N-(3-oxo-3,4-dihydro-2-quinoxalinyl)hydrazone
500mg
$ 918.00

Total 1 raw suppliers

Chemical Property of 3-[2-[(4-fluorophenyl)methylidene]hydrazinyl]-1H-quinoxalin-2-one

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:282.09168915
Heavy Atom Count:21
Complexity:443

Purity/Quality:: 4-Fluorobenzenecarbaldehyde N-(3-oxo-3,4-dihydro-2-quinoxalinyl)hydrazone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=O)C(=N2)NN=CC3=CC=C(C=C3)F

Technology Process of 3-[2-[(4-fluorophenyl)methylidene]hydrazinyl]-1H-quinoxalin-2-one

There total 3 articles about 3-[2-[(4-fluorophenyl)methylidene]hydrazinyl]-1H-quinoxalin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 31595-63-8
3-hydrazineylidene-3,4-dihydroquinoxalin-2(1H)-one

: 459-57-4
4-fluorobenzaldehyde

: 129227-27-6
3-{N'-[1-(4-Fluoro-phenyl)-meth-(E)-ylidene]-hydrazino}-1H-quinoxalin-2-one

Guidance literature:: In ethanol; for 5h; Heating;
DOI:10.1002/jhet.5570270339

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 129227-27-6
3-{N'-[1-(4-Fluoro-phenyl)-meth-(E)-ylidene]-hydrazino}-1H-quinoxalin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / 4 h / Reflux

2: hydrazine hydrate / 2 h / Reflux

3: ethanol / 2 h / Reflux

With hydrogenchloride; hydrazine hydrate; In ethanol; water;
DOI:10.1016/j.bioorg.2019.102932

Reference yield:

: 15804-19-0,6287-20-3
quinoxaline-2,3-dione

: 129227-27-6
3-{N'-[1-(4-Fluoro-phenyl)-meth-(E)-ylidene]-hydrazino}-1H-quinoxalin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / 2 h / Reflux

2: ethanol / 2 h / Reflux

With hydrazine hydrate; In ethanol;
DOI:10.1016/j.bioorg.2019.102932