1-N-BOC-(2R,4R)-4-HYDROXY-2-(HYDROXYMETHYL) PIPERIDINE

Base Information

Chemical Name:1-N-BOC-(2R,4R)-4-HYDROXY-2-(HYDROXYMETHYL) PIPERIDINE
CAS No.:1029429-49-9
Molecular Formula:C₁₁H₂₁NO₄
Molecular Weight:231.292
Hs Code.:
Mol file:1029429-49-9.mol

Synonyms:(2S,4R)-4-hydroxy-2-hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of 1-N-BOC-(2R,4R)-4-HYDROXY-2-(HYDROXYMETHYL) PIPERIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1-N-BOC-(2R,4R)-4-HYDROXY-2-(HYDROXYMETHYL) PIPERIDINE

Chemical Property:

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:

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Technology Process of 1-N-BOC-(2R,4R)-4-HYDROXY-2-(HYDROXYMETHYL) PIPERIDINE

There total 2 articles about 1-N-BOC-(2R,4R)-4-HYDROXY-2-(HYDROXYMETHYL) PIPERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 254882-06-9,181269-87-4
(2S,4R)-methyl 1-(tert-butoxycarbonyl)-4-hydroxypiperidine-2-carboxylate

: 1029429-49-9
(2S,4R)-4-hydroxy-2-hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: (2S,4R)-methyl 1-(tert-butoxycarbonyl)-4-hydroxypiperidine-2-carboxylate; With sodium tetrahydroborate; In ethanol; at 0 ℃; for 20h;

With sodium hydroxide; water; In ethanol;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: (2S,4R)-2-hydroxymethylpiperidin-4-ol

: 1029429-49-9
(2S,4R)-4-hydroxy-2-hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 20h;

Reference yield:

: 1029429-49-9
(2S,4R)-4-hydroxy-2-hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester

: 58479-61-1
tert-butylchlorodiphenylsilane

: 2-(tert-butyl-diphenyl-silanyloxymethyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: (2S,4R)-4-hydroxy-2-hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester; With sodium tetrahydroborate; In ethanol; at 0 ℃;

With sodium hydroxide; In ethanol; water;

tert-butylchlorodiphenylsilane; With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 20h;