Technology Process of Potassium; (1S,2R)-1-hydrazinocarbonyl-2-[3-(2-methoxy-ethoxymethoxy)-phenyl]-cyclopropanecarboxylate
There total 5 articles about Potassium; (1S,2R)-1-hydrazinocarbonyl-2-[3-(2-methoxy-ethoxymethoxy)-phenyl]-cyclopropanecarboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 70 percent / aq. NaOH, Aliquat 336 / CH2Cl2 / Ambient temperature
2: 89 percent / piperidine, acetic acid / toluene / Heating
3: 1.) NaH / 1.) DMSO, RT, 30 min, 2.) THF a) RT, 1 h, b) 50 - 60 deg C, 1 h
4: 95.6 percent / aq. NaOH / ethanol / 40 h / Ambient temperature
5: 1.) KOH, 2.) aq. N2NNH2 / 1.) EtOH, RT, 1 h, 2.) EtOH, reflux, 36 h
With
piperidine; potassium hydroxide; sodium hydroxide; azido amine; Aliquat 336; sodium hydride; acetic acid;
In
ethanol; dichloromethane; toluene;
DOI:10.1021/jm00086a009
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 89 percent / piperidine, acetic acid / toluene / Heating
2: 1.) NaH / 1.) DMSO, RT, 30 min, 2.) THF a) RT, 1 h, b) 50 - 60 deg C, 1 h
3: 95.6 percent / aq. NaOH / ethanol / 40 h / Ambient temperature
4: 1.) KOH, 2.) aq. N2NNH2 / 1.) EtOH, RT, 1 h, 2.) EtOH, reflux, 36 h
With
piperidine; potassium hydroxide; sodium hydroxide; azido amine; sodium hydride; acetic acid;
In
ethanol; toluene;
DOI:10.1021/jm00086a009
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) NaH / 1.) DMSO, RT, 30 min, 2.) THF a) RT, 1 h, b) 50 - 60 deg C, 1 h
2: 95.6 percent / aq. NaOH / ethanol / 40 h / Ambient temperature
3: 1.) KOH, 2.) aq. N2NNH2 / 1.) EtOH, RT, 1 h, 2.) EtOH, reflux, 36 h
With
potassium hydroxide; sodium hydroxide; azido amine; sodium hydride;
In
ethanol;
DOI:10.1021/jm00086a009
