Technology Process of N-(3-((3,5-dimethylphenyl)amino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-3-nitrobenzenesulfonamide
There total 2 articles about N-(3-((3,5-dimethylphenyl)amino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-3-nitrobenzenesulfonamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
N-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-3-nitrobenzenesulfonamide;
With
cerium(III) chloride heptahydrate;
In
methanol;
at 20 ℃;
for 1.5h;
Microwave irradiation;
3,5-dimethylaminoaniline;
In
methanol;
at 90 ℃;
for 16h;
Sealed tube;
Microwave irradiation;
DOI:10.1016/j.bmc.2014.03.015
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 20 °C / Sealed tube; Microwave irradiation
2.1: cerium(III) chloride heptahydrate / methanol / 1.5 h / 20 °C / Microwave irradiation
2.2: 16 h / 90 °C / Sealed tube; Microwave irradiation
With
cerium(III) chloride heptahydrate; caesium carbonate;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2014.03.015
