N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate

Base Information

• Chemical Name: N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate
• CAS No.: 1387526-38-6
• Molecular Formula: C₂H₂O₄*C₂₁H₂₉NO
• Molecular Weight: 401.503
• Mol file: 1387526-38-6.mol

Synonyms:N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate

Chemical Property of N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate

There total 2 articles about N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

1-Bromo-3-phenylpropane (637-59-2) + 2-(methyl(3-phenylpropyl)amino)ethanol (37082-04-5) + oxalic acid (144-62-7,97993-78-7) → N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate (1387526-38-6)

Guidance literature:

1-Bromo-3-phenylpropane; 2-(methyl(3-phenylpropyl)amino)ethanol; With potassium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

oxalic acid; In diethyl ether; Inert atmosphere;

DOI:10.1016/j.bmc.2012.05.006

Reference yield:

1-Bromo-3-phenylpropane (637-59-2) → N-methyl-N-phenylpropyl-2-(3-phenylpropoxy)ethanamine oxalate (1387526-38-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2.1: potassium hydroxide / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

2.2: Inert atmosphere

With potassium carbonate; potassium hydroxide; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2012.05.006

upstream raw materials:

1-Bromo-3-phenylpropane

2-(methyl(3-phenylpropyl)amino)ethanol

oxalic acid