N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide

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Chemical Name:N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide
CAS No.:1190758-12-3
Molecular Formula:C₄₀H₅₀N₂O₆
Molecular Weight:654.847
Hs Code.:

Synonyms:N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide

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Chemical Property of N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide

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Technology Process of N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide

There total 1 articles about N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 1185870-87-4
(4S,5R)-5-(4-(benzyloxy)-benzyl)-4-(benzyloxy)pyrrolidin-2-one

: 1190758-11-2
pentafluorophenyl (E)-5-(6,6-dimethylheptanamido)-3-methoxypent-2-enoate

: 1190758-12-3
N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide

Guidance literature:: (4S,5R)-5-(4-(benzyloxy)-benzyl)-4-(benzyloxy)pyrrolidin-2-one; With n-butyllithium; In tetrahydrofuran; hexane; at -80 ℃; for 0.25h;

pentafluorophenyl (E)-5-(6,6-dimethylheptanamido)-3-methoxypent-2-enoate; In tetrahydrofuran; hexane; at -80 - -5 ℃;
DOI:10.1021/jo901557h

Reference yield: 86.0%

: 1190758-12-3
N-[(E)-5-((2R,3S)-2-(4-(benzyloxy)benzyl)-3-(benzyloxy)-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide

: 1190757-98-2
N-[(E)-5-((2R,3S)-2-(4-hydroxybenzyl)-3-hydroxy-5-oxopyrrolidin-1-yl)-3-methoxy-5-oxopent-3-enyl]-6,6-dimethylheptanamide

Guidance literature:: With formic acid; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 5h; Inert atmosphere;
DOI:10.1021/jo901557h