dimethylcyclohexa-2,4-dienylmalonate

Base Information

• Chemical Name: dimethylcyclohexa-2,4-dienylmalonate
• CAS No.: 104307-70-2
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 210.23
• Mol file: 104307-70-2.mol

Synonyms:dimethylcyclohexa-2,4-dienylmalonate

Chemical Property of dimethylcyclohexa-2,4-dienylmalonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethylcyclohexa-2,4-dienylmalonate

There total 12 articles about dimethylcyclohexa-2,4-dienylmalonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dimethyl (4-fluorocyclohex-2-en-1-yl)malonate → dimethyl (2,4-cyclohexadien-1-yl)malonate (104307-70-2)

Guidance literature:

With tetrakis(triphenylphosphine)platinum; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1021/om201029m

Reference yield: 69.0%

syn-4-fluorocyclohex-2-en-1-yl methyl carbonate + malonic acid dimethyl ester (108-59-8) → dimethyl (2,4-cyclohexadien-1-yl)malonate (104307-70-2) + C12H18O5 + cis-1,4-bis(dicarboxymethyl)cyclohex-2-ene

Guidance literature:

malonic acid dimethyl ester; With sodium hydride; In tetrahydrofuran;

syn-4-fluorocyclohex-2-en-1-yl methyl carbonate; With tetrakis(triphenylphosphine)platinum; In tetrahydrofuran; at 20 ℃; for 10h; stereoselective reaction;

DOI:10.1021/om201029m

Reference yield: 39.0%

4-fluorocyclohex-2-en-1-yl acetate + malonic acid dimethyl ester (108-59-8) → dimethyl (2,4-cyclohexadien-1-yl)malonate (104307-70-2) + C12H18O5 + cis-1,4-bis(dicarboxymethyl)cyclohex-2-ene

Guidance literature:

malonic acid dimethyl ester; With sodium hydride; In tetrahydrofuran;

4-fluorocyclohex-2-en-1-yl acetate; With tetrakis(triphenylphosphine)platinum; In tetrahydrofuran; at 20 ℃; for 24h; stereoselective reaction;

DOI:10.1021/om201029m

upstream raw materials:

cis-1-acetoxy-4-(dicarbomethoxymethyl)-2-cyclohexene

malonic acid dimethyl ester

cis-(1R,4S)-1-Acetoxy-4--2-cyclohexene

acetic acid (1S,4R)-(-)-4-hydroxycyclohex-2-enyl ester

Downstream raw materials:

(2,4-cyclohexadienyl)-acetic acid

dimethyl (2,4-cyclohexadienyl)((E)-4-acetoxy-2-butenyl)malonate

dimethyl (2,4-cyclohexadienyl)((Z)-4-acetoxy-2-butenyl)malonate

dimethyl (2,4-cyclohexadien-1-yl)(2-propyn-1-yl)malonate