2-BROMO-4-NITROBENZOIC ACID

Base Information

• Chemical Name: 2-BROMO-4-NITROBENZOIC ACID
• CAS No.: 16426-64-5
• Molecular Formula: C7H4BrNO4
• Molecular Weight: 246.017
• Hs Code.: 2916399090
• Mol file: 16426-64-5.mol

Synonyms:2-Bromo-4-nitrobenzoicacid;NSC 227965;2-bromo-4-nitrobenzoic acid;

Chemical Property of 2-BROMO-4-NITROBENZOIC ACID

Chemical Property:

• Appearance/Colour: light brown solid
• Vapor Pressure: 1.67E-06mmHg at 25°C
• Melting Point: 165-168 °C
• Refractive Index: 1.65
• Boiling Point: 381.6 °C at 760 mmHg
• PKA: 1.98±0.13(Predicted)
• Flash Point: 184.6°C
• PSA: 83.12000
• Density: 1.892
• LogP: 2.57870
• Storage Temp.: Keep Cold
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Bromo-4-nitrobenzoic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-4-NITROBENZOIC ACID

There total 5 articles about 2-BROMO-4-NITROBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-bromo-4-nitrotoluene (7745-93-9) → 2-bromo-4-nitrobenzoic acid (16426-64-5)

Guidance literature:

With potassium permanganate; In pyridine; water; for 5h; Heating;

DOI:10.1016/S0968-0896(99)00252-7

Reference yield:

→ 2-bromo-4-nitrobenzoic acid (16426-64-5)

Guidance literature:

With bromine; nachfolgend Verseifen;

Reference yield:

4-nitrophthalic acid (610-27-5) → 2-bromo-4-nitrobenzoic acid (16426-64-5)

Guidance literature:

DOI:10.1007/BF02809646

upstream raw materials:

4-nitrophthalic acid

2-bromo-4-nitrotoluene

Downstream raw materials:

2-hydroxy-4-nitrobenzoic acid

2-bromo-4-aminobenzoic acid

2-bromo-4-nitrobenzoyl chloride

carbon dioxide

Refernces

• 1、 Pump, Eva,Poater, Albert,Zirngast, Michaela,Torvisco, Ana,Fischer, Roland,Cavallo, Luigi,Slugovc, Christian. "Impact of electronic modification of the chelating benzylidene ligand in cis-dichloro-configured second-generation olefin metathesis catalysts on their activity". . p. 2806 - 2813. Retrieved 2014/06/24.
• 2、 -. "NOVEL MACROCYCLES AS FACTOR XIA INHIBITORS". Paragraph 00355. . Retrieved 2013/03/26.