2-BROMO-4-AMINOBENZOIC ACID

Base Information

• Chemical Name: 2-BROMO-4-AMINOBENZOIC ACID
• CAS No.: 2486-52-4
• Molecular Formula: C7H6 Br N O2
• Molecular Weight: 216.034
• Hs Code.: 2922499990
• Mol file: 2486-52-4.mol

Synonyms:2-Bromo-4-aminobenzoicacid; 4-Amino-2-bromobenzoic acid; NSC 293902

Chemical Property of 2-BROMO-4-AMINOBENZOIC ACID

Chemical Property:

• Vapor Pressure: 2.9E-06mmHg at 25°C
• Melting Point: 198-200°C
• Boiling Point: 374.2°Cat760mmHg
• PKA: 3.51±0.10(Predicted)
• Flash Point: 180.1°C
• PSA: 63.32000
• Density: 1.793g/cm³
• LogP: 2.31070
• Storage Temp.: Refrigerator
• Solubility.: Methanol, Water

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-4-aminobenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-4-AMINOBENZOIC ACID

There total 7 articles about 2-BROMO-4-AMINOBENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-bromo-4-nitrobenzoic acid (16426-64-5) → 2-bromo-4-aminobenzoic acid (2486-52-4)

Guidance literature:

With ethanol; tin(ll) chloride; for 1h; Reflux;

DOI:10.1002/anie.200705313

Reference yield:

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 2-bromo-4-aminobenzoic acid (2486-52-4)

Guidance literature:

With tetrachloromethane; N-Bromosuccinimide;

Reference yield:

2-bromo-4-acetamidobenzoic acid (55415-33-3) → 2-bromo-4-aminobenzoic acid (2486-52-4)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

2-bromo-4-acetamidobenzoic acid

2-bromo-4-nitrobenzoic acid

4-amino-benzoic acid

magnesium sulfate

Downstream raw materials:

4-amino-2-bromo-benzoic acid-(2-diethylamino-ethyl ester)

4-(N'-allyl-thioureido)-2-bromo-benzoic acid

ethyl-2-bromo-4-amino-benzoate

2-(benzo[d]thiazol-2-yl)-[1,1′-biphenyl]-5-amine