1-(4-Chlorophenyl)-3-(5-cyclopropyl-2-phenylpyrazol-3-yl)urea

Base Information

Chemical Name:1-(4-Chlorophenyl)-3-(5-cyclopropyl-2-phenylpyrazol-3-yl)urea
CAS No.:4760-61-6
Molecular Formula:C₂₂H₁₉NO
Molecular Weight:313.399
Hs Code.:
DSSTox Substance ID:DTXSID00384791
Wikidata:Q82177150

Synonyms:4760-61-6;1-(4-chlorophenyl)-3-(5-cyclopropyl-2-phenylpyrazol-3-yl)urea;ZINC01037296;Oprea1_690884;SCHEMBL13234475;DTXSID00384791;CCG-40657;EN300-22548114;SR-01000630783-1;1-(4-chlorophenyl)-3-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)urea;852670-38-3

Suppliers and Price of 1-(4-Chlorophenyl)-3-(5-cyclopropyl-2-phenylpyrazol-3-yl)urea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(4-Chlorophenyl)-3-(5-cyclopropyl-2-phenylpyrazol-3-yl)urea

Chemical Property:

Vapor Pressure:5.57E-08mmHg at 25°C
Boiling Point:441.2°C at 760 mmHg
Flash Point:220.6°C
Density:1.37g/cm³
XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:352.1090889
Heavy Atom Count:25
Complexity:458

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1C2=NN(C(=C2)NC(=O)NC3=CC=C(C=C3)Cl)C4=CC=CC=C4

Technology Process of 1-(4-Chlorophenyl)-3-(5-cyclopropyl-2-phenylpyrazol-3-yl)urea

There total 6 articles about 1-(4-Chlorophenyl)-3-(5-cyclopropyl-2-phenylpyrazol-3-yl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4397-53-9
p-benzyloxybenzaldehyde

: 7677-24-9
trimethylsilyl cyanide

: 4294-57-9
para-methylphenylmagnesium bromide

: 4760-61-6
<4-Benzyloxy-phenyl>-p-tolyl-acetonitril

Guidance literature:: p-benzyloxybenzaldehyde; para-methylphenylmagnesium bromide; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Inert atmosphere;

trimethylsilyl cyanide; With indium(III) chloride; In dichloromethane; at 0 ℃;
DOI:10.1021/acs.orglett.1c02640

Reference yield:

: 5339-06-0
4-formylphenyl benzoate

: 4760-61-6
<4-Benzyloxy-phenyl>-p-tolyl-acetonitril

Guidance literature:: Multi-step reaction with 2 steps

1: BF₃

2: (i) NaOEt, EtOH, (ii) /BRN= 471308/

With boron trifluoride;
DOI:10.1021/jm00341a014

Reference yield:

: 108-88-3,15644-74-3,16713-13-6
toluene

: 4760-61-6
<4-Benzyloxy-phenyl>-p-tolyl-acetonitril

Guidance literature:: Multi-step reaction with 2 steps

1: BF₃

2: (i) NaOEt, EtOH, (ii) /BRN= 471308/

With boron trifluoride;
DOI:10.1021/jm00341a014