2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol

Base Information

• Chemical Name: 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol
• CAS No.: 1095945-99-5
• Molecular Formula: C₃₄H₃₇N₇O
• Molecular Weight: 559.714
• Mol file: 1095945-99-5.mol

Synonyms:2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol

Chemical Property of 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol

There total 3 articles about 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.3%

C39H45N7O3 (1095946-08-9) → 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol (1095945-99-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1002/chem.200801260

Reference yield:

tyrosamine (51-67-2) → 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol (1095945-99-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / methanol

2.2: Reflux

3.1: trifluoroacetic acid / dichloromethane

With potassium carbonate; trifluoroacetic acid; In methanol; dichloromethane;

DOI:10.1002/anie.201105565

Reference yield:

N-t-butoxycarbonyl-tyramine (64318-28-1) → 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol (1095945-99-5)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 144 h / Reflux

2: trifluoroacetic acid / dichloromethane

With trifluoroacetic acid; In ethanol; dichloromethane;

DOI:10.1039/d0dt00930j

upstream raw materials:

C₃₉H₄₅N₇O₃

tyrosamine

N-t-butoxycarbonyl-tyramine

Downstream raw materials:

C₄₉H₅₀N₁₀O₂