1-(4-fluorophenyl)-1H-pyrazol-4-amine

Base Information

Chemical Name:1-(4-fluorophenyl)-1H-pyrazol-4-amine
CAS No.:1156602-69-5
Molecular Formula:C₉H₈FN₃
Molecular Weight:177.181
Hs Code.:
European Community (EC) Number:866-367-1

Synonyms:1-(4-fluorophenyl)-1H-pyrazol-4-amine;1156602-69-5;1-(4-fluorophenyl)pyrazol-4-amine;SCHEMBL15779430;UBKWWOPAKRZWTI-UHFFFAOYSA-N;MFCD12192664;AKOS009581179;AB65396;(4-fluorophenyl)-1 h -pyrazol-4-amine;AM20020243;CS-0258602;EN300-70596;F73744;Z431510022

Suppliers and Price of 1-(4-fluorophenyl)-1H-pyrazol-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-Fluorophenyl)-1H-pyrazol-4-amine 97%
10g
$ 1488.00

Crysdot
1-(4-Fluorophenyl)-1H-pyrazol-4-amine 97%
5g
$ 1191.00

AK Scientific
1-(4-Fluorophenyl)-1H-pyrazol-4-amine
5g
$ 1772.00

Total 4 raw suppliers

Chemical Property of 1-(4-fluorophenyl)-1H-pyrazol-4-amine

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:177.07022543
Heavy Atom Count:13
Complexity:168

Purity/Quality:

98%min ^*data from raw suppliers

1-(4-Fluorophenyl)-1H-pyrazol-4-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1N2C=C(C=N2)N)F

Technology Process of 1-(4-fluorophenyl)-1H-pyrazol-4-amine

There total 4 articles about 1-(4-fluorophenyl)-1H-pyrazol-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 957062-56-5
4-bromo-1-(4-fluorophenyl)-1H-pyrazole

: 1156602-69-5
4-amino-1-(4-fluorophenyl)-1H-pyrazole

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2-(di-1-adamantylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl; ammonia; sodium t-butanolate; In 1,4-dioxane; at 120 ℃; for 20h; Reagent/catalyst; Inert atmosphere;
DOI:10.1021/ol401612c

Reference yield: 63.0%

: 924709-31-9
1-(4-fluorophenyl)-4-nitro-1H-pyrazole

: 1156602-69-5
4-amino-1-(4-fluorophenyl)-1H-pyrazole

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; ethyl acetate; for 1h; under 2068.65 Torr;

Reference yield:

: 352-34-1
4-fluoro-1-iodobenzene

: 1156602-69-5
4-amino-1-(4-fluorophenyl)-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: 8-quinolinol; copper(l) iodide; potassium carbonate / dimethyl sulfoxide / 135 °C

2: palladium 10% on activated carbon; hydrogen / ethyl acetate; ethanol / 1 h / 2068.65 Torr

With copper(l) iodide; 8-quinolinol; palladium 10% on activated carbon; hydrogen; potassium carbonate; In ethanol; dimethyl sulfoxide; ethyl acetate;