2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

Base Information

Chemical Name:2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester
CAS No.:98911-45-6
Molecular Formula:C₁₈H₂₃NO₅
Molecular Weight:333.384
Hs Code.:

Synonyms:2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

Suppliers and Price of 2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

There total 8 articles about 2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 98911-44-5
N-<2-(tert-Butoxycarbonylmethyl)-4-methoxy-5-methylphenyl>succinamsaeure

: 98911-45-6
2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In dichloromethane; for 15h; Ambient temperature;
DOI:10.1002/jlac.198519850711

Reference yield:

: 95-87-4
2,5-Dimethylphenol

: 98911-45-6
2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

Guidance literature:: Multi-step reaction with 8 steps

1: sodium nitrite, conc. H₂SO₄ / acetic acid; H₂O / 0.17 h / 8 - 10 °C

2: 68percent HNO₃ / H₂O / 0.25 h / 45 °C

3: 58 percent / NaOH / H₂O / 2 h / 40 - 45 °C

4: 1) KOtBu, 2) 10percent H₂O₂, 3N NaOH / 1) benzene; 24h, reflux; 24h, r.t.

5: 76 percent / 60percent HClO₄ / 12 h / Ambient temperature

6: H₂ / 10percent Pd/C / ethyl acetate / 48 h / 735.5 Torr / Ambient temperature

7: 81 percent / dioxane; pyridine / 14 h / 5 °C

8: 96 percent / 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH₂Cl₂ / 15 h / Ambient temperature

With sodium hydroxide; perchloric acid; sulfuric acid; potassium tert-butylate; hydrogen; dihydrogen peroxide; nitric acid; benzotriazol-1-ol; dicyclohexyl-carbodiimide; sodium nitrite; palladium on activated charcoal; In 1,4-dioxane; pyridine; dichloromethane; water; acetic acid; ethyl acetate;
DOI:10.1002/jlac.198519850711

Reference yield:

: 3139-06-8
1-methoxy-2,5-dimethyl-4-nitrobenzene

: 98911-45-6
2-<2-(2,5-Dioxo-1-pyrrolidinyl)-5-methoxy-4-methylphenyl>essigsaeure-tert-butylester

Guidance literature:: Multi-step reaction with 5 steps

1: 1) KOtBu, 2) 10percent H₂O₂, 3N NaOH / 1) benzene; 24h, reflux; 24h, r.t.

2: 76 percent / 60percent HClO₄ / 12 h / Ambient temperature

3: H₂ / 10percent Pd/C / ethyl acetate / 48 h / 735.5 Torr / Ambient temperature

4: 81 percent / dioxane; pyridine / 14 h / 5 °C

5: 96 percent / 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CH₂Cl₂ / 15 h / Ambient temperature

With sodium hydroxide; perchloric acid; potassium tert-butylate; hydrogen; dihydrogen peroxide; benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium on activated charcoal; In 1,4-dioxane; pyridine; dichloromethane; ethyl acetate;
DOI:10.1002/jlac.198519850711