6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Base Information

Chemical Name:6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one
CAS No.:1613720-62-9
Molecular Formula:C₃₅H₄₁F₃N₄O₄Si
Molecular Weight:666.816
Hs Code.:

6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Synonyms:6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Suppliers and Price of 6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

There total 5 articles about 6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 1613720-61-8
6-hydroxy-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

: 133891-87-9
methanesulfonic acid 1-benzhydryl-3-methylazetidin-3-yl ester

: 1613720-62-9
6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 80 ℃;

Reference yield:

: 1613719-81-5
6-bromo-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

: 1613720-62-9
6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 90 °C

2: dihydrogen peroxide / 1,4-dioxane; acetic acid / 20 °C

3: caesium carbonate / N,N-dimethyl-formamide / 80 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; dihydrogen peroxide; potassium acetate; caesium carbonate; In 1,4-dioxane; acetic acid; N,N-dimethyl-formamide;

Reference yield:

: 320-49-0
3-trifluoromethyl-4-bromophenol

: 1613720-62-9
6-(1-benzhydryl-3-methylazetidin-3-yloxy)-4-methyl-7-trifluoromethyl-2-(2-trimethylsilanylethoxymethyl)-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one

Guidance literature:: Multi-step reaction with 8 steps

1.1: sulfuric acid; nitric acid / acetic acid / 3.5 h / 0 - 20 °C

2.1: zinc; ammonium chloride / methanol / 20 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

3.2: 3 h / 20 °C

4.1: Lawessons reagent / toluene / 1 h / Reflux

4.2: 1 h / 80 °C

5.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h

5.2: 2 h / 20 °C

6.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 90 °C

7.1: dihydrogen peroxide / 1,4-dioxane; acetic acid / 20 °C

8.1: caesium carbonate / N,N-dimethyl-formamide / 80 °C

With Lawessons reagent; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sulfuric acid; dihydrogen peroxide; nitric acid; potassium acetate; sodium hydride; potassium carbonate; ammonium chloride; caesium carbonate; zinc; In tetrahydrofuran; 1,4-dioxane; methanol; acetic acid; N,N-dimethyl-formamide; toluene; mineral oil;