3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate

Base Information

Chemical Name:3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate
CAS No.:1035265-79-2
Molecular Formula:C₁₇H₁₅BrFN₃O₄S
Molecular Weight:456.292
Hs Code.:

Synonyms:3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate

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Chemical Property of 3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate

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Technology Process of 3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate

There total 1 articles about 3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1035266-82-0
3-[4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-2-thioxoimidazoIidin-4-yl]phenyl methanesulfonate

: 1035265-79-2
3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate

Guidance literature:: With tert.-butylhydroperoxide; ammonia; In methanol; water; at 20 ℃;

Reference yield: 9.0%

: tributyl-(4-methoxypyrimidin-2-yl)stannane

: 1035265-79-2
3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate

: 1035265-77-0
3-{2-amino-4-[4-fluoro-3-(4-methoxypyrimidin-2-yl)phenyl]-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl}phenyl methanesulfonate

Guidance literature:: bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 130 ℃; for 13h; Irradiation in a microwave;

Reference yield: 6.2%

: 937595-70-5
(5-chloro-2-fluoropyridin-3-yl)boronic acid

: 1035265-79-2
3-[2-amino-4-(3-bromo-4-fluorophenyl)-1-methyl-5-oxo-4,5-dihydro-1H-imidazoI-4-yl]phenyl methanesulfonate

: 1035266-51-3
3-{2-amino-4-[3-(5-chloro-2-fluoropyridin-3-yl)-4-fluorophenyl]-1-methyl-5-oxo-4,5-dihydro-1H-imidazol-4-yl}phenyl methanesulfonate

Guidance literature:: With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; at 130 ℃; for 2h; Irradiation in a microwave;