p-MPPI

Base Information

Chemical Name:p-MPPI
CAS No.:155204-23-2
Molecular Formula:C25H27 I N4 O2
Molecular Weight:542.419
Hs Code.:
DSSTox Substance ID:DTXSID70165857
Nikkaji Number:J621.833D
Wikidata:Q27078091
Pharos Ligand ID:Q8DMQ7SR27BX
ChEMBL ID:CHEMBL29027
Mol file:155204-23-2.mol

Synonyms:4-(2'-methoxyphenyl)-1-(2'-(N-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine;4-MPPI;p-MPPI

Suppliers and Price of p-MPPI

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-IODO-N-(2-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-ETHYL)-N-PYRIDIN-2-YL-BENZAMIDE 95.00%
50MG
$ 1217.56

American Custom Chemicals Corporation
4-IODO-N-(2-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-ETHYL)-N-PYRIDIN-2-YL-BENZAMIDE 95.00%
10MG
$ 267.75

Total 2 raw suppliers

Chemical Property of p-MPPI

Chemical Property:

Vapor Pressure:3.66E-17mmHg at 25°C
Boiling Point:657.5°C at 760 mmHg
Flash Point:351.4°C
PSA：48.91000
Density:1.46g/cm³
LogP:4.16670
Solubility.:H2O: 2.4 mg/mL
XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:542.11787
Heavy Atom Count:32
Complexity:578

Purity/Quality:

99% ^*data from raw suppliers

4-IODO-N-(2-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-ETHYL)-N-PYRIDIN-2-YL-BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCN(CC2)CCN(C3=CC=CC=N3)C(=O)C4=CC=C(C=C4)I

Technology Process of p-MPPI

There total 6 articles about p-MPPI which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 146714-63-8
4-(2-methoxyphenyl)-1-(2-pyridinylaminocarbonyl)methylpiperazine

: 155204-23-2
4-iodo-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-pyridin-2-ylbenzylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / LiAlH₄ / tetrahydrofuran

2: 88 percent / Et₃N / acetonitrile

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; acetonitrile;
DOI:10.1021/ja067276c

Reference yield:

: 504-29-0
2-aminopyridine

: 155204-23-2
4-iodo-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-pyridin-2-ylbenzylamide

Guidance literature:: Multi-step reaction with 4 steps

1: 56 percent / acetonitrile

2: 83 percent / K₂CO₃ / dimethylformamide

3: 90 percent / LiAlH₄ / tetrahydrofuran

4: 88 percent / Et₃N / acetonitrile

With lithium aluminium tetrahydride; potassium carbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja067276c

Reference yield:

: 929039-11-2
chloro-acetic acid-[2]pyridylamide; hydrochloride

: 155204-23-2
4-iodo-N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-pyridin-2-ylbenzylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / K₂CO₃ / dimethylformamide

2: 90 percent / LiAlH₄ / tetrahydrofuran

3: 88 percent / Et₃N / acetonitrile

With lithium aluminium tetrahydride; potassium carbonate; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja067276c